Method for verifying the calculated radiation dose of an ion beam therapy system

• US 6,799,068 B1
• Filed: 11/13/2001
• Issued: 09/28/2004
• Est. Priority Date: 02/19/1999
• Status: Expired due to Term

• Current Assignee: Gessellschaft Fur Schwerionenforschung MbH
• Original Assignee: Gessellschaft Fur Schwerionenforschung MbH
• Inventors: Hartmann, Gunther, Karger, Christian, Jaekel, Oliver, Heeg, Peter
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US09/890,896
• Time in Patent Office: 1,050 Days
• Field of Search: 250/251, 250/252.1, 250/492.1, 250/492.3, 250/306, 250/307, 250/492.21, 250/505.1, 128/898, 607/2, 607/3, 600/436, 315/501, 315/505
• US Class Current: 607/2
• CPC Class Codes: A61N 2005/1076 using a dummy object placed in the radiation field, e.g. phantom
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1071 for verifying the dose delivered by the treatment plan

Abstract

A method for the verification of the calculated radiation dose of an ion beam therapy system that comprises a grid scanner device, arranged in a beam guidance system (6, 8), having vertical deflection means (13) and horizontal deflection means (14) for the vertical and horizontal deflection of a treatment beam (11) perpendicular to its beam direction, with the result that the treatment beam (11) is deflected by the grid scanner device to an isocentre (10) of the irradiation site and scans a specific area surrounding the isocentre (10), irradiation being carried out on the basis of automatically calculated radiation dose data. The accuracy of the calculation of the radiation dose data is verified by using a phantom, a discrepancy between the radiation dose calculated for the at least one measurement point of the phantom and a radiation dose measured for the at least one measurement point being determined and evaluated.

Claims

1. Method for the verification of a calculated radiation dose of a heavy ion beam therapy system,

wherein the heavy ion beam therapy system comprises:

at least one ion source (1) for heavy ions,

an accelerator device (2, 5) for the acceleration of the ions of the ion source (1) in the form of a treatment beam (11),

a beam guidance system (6, 8) to guide the treatment beam (11) from the accelerator device (2, 5) to at least one irradiation site for treatment of a patient, the beam guidance system (6, 8) comprising at least one beam guidance channel (6), and

a grid scanner device, arranged in the beam guidance system (6, 8), having a vertical deflection means (13) and horizontal deflection means (14) for the vertical and horizontal deflection of the treatment beam (11) perpendicular to its beam direction, with the result that the treatment beam (11) is deflected by the grid scanner device to an isocentre (10) of the irradiation site and scans a specific area surrounding the isocentre (10), and

wherein irradiation is carried out on the basis of calculated radiation dose data and the accuracy of the calculation of the radiation dose data is verified by using a phantom with the aid of the following steps;

a) the radiation dose data are calculated for a plurality of specific measurement points in the phantom,

b) irradiation of the phantom is carried out using the calculated radiation dose, and at the measurement points the radiation dose brought about there is measured, values ascertained by ionization chambers being converted into energy does values for verification of the calculated dose values,

c) the discrepancy between the radiation dose calculated for the measurement points and the radiation dose measured for the measurement points is determined, and

d) it is concluded that the accuracy of the calculation of the radiation dose data is adequate if the average discrepancy, for al the measurement points, between the calculated and the measured radiation dose values does not exceed a predetermined first tolerance value of ±

5% and, for each individual measurement point, the discrepancy between the radiation dose calculated and measured for that measurement point does not exceed a predetermined second tolerance value of ±

7%.

2. Method according to claim 1, wherein in step b) the radiation dose is measured with the aid of an appropriately positioned ionization chamber.

3. Method according to claim 1, wherein the accuracy of the calculation of the radiation dose data is verified, for a homogeneous medium to be irradiated, by using a water phantom.

4. Method according to claim 1, wherein the accuracy of the calculation of the radiation dose data is verified, for a non-homogeneous medium to be irradiated, by using a solid-body phantom having non-homogeneities.

5. Method according to claim 4, wherein the solid body phantom is spherical and consists of a water-equivalent material.

6. Method according to claim 4, wherein different non-homogeneities are interchangeably inserted in the solid-body phantom.

7. Method according to claim 4, wherein the steps a)-d) are carried out for at least three different non-homogeneity structures of the solid-body phantom, the first solid-body phantom having boundary layers between different materials, the second solid-body phantom having thin non-homogeneities and the third solid-body phantom having thick non-homogeneities.

8. Method according to claim 1, wherein the accuracy of the calculation of the radiation dose data is verified by using an irregularly shaped phantom.

9. Method according to claim 8, wherein the irregularly shaped phantom consists of a water-equivalent material and has the shape of a human head.

10. Method according to claim 1, wherein

a digital reconstruction of the phantom is calculated;

an image of the phantom is produced and compared with the calculated reconstructions to ascertain a discrepancy; and

it is concluded that there is an error in the calculation of the digital reconstructions if the discrepancy between the calculated reconstructions and the corresponding image exceeds a specific tolerance limit value.

11. Method according to claim 10, wherein a plurality of digital X-ray reconstructions of the phantom are calculated;

and X-ray images of the phantom are produced from a plurality of imaging directions and individually compared with the corresponding X-ray reconstructions.

12. Method according to claim 10, wherein the tolerance limit value is 2 mm.

13. Method according to claim 1, wherein said heavy ions are carbon ions.