Safety injectors

• US 6,808,507 B2
• Filed: 05/10/2002
• Issued: 10/26/2004
• Est. Priority Date: 05/10/2002
• Status: Expired due to Fees

• Current Assignee: Nova Bio-Pharma Technologies Limited
• Original Assignee: Cambridge Biostability Limited (Nova Bio-Pharma Holdings Ltd.)
• Inventors: Roser, Bruce J.
• Primary Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US10/141,968
• Publication Number:
  US 20030212362A1
• Time in Patent Office: 900 Days
• Field of Search: 604/110, 604/195, 604/198, 604/218, 604/232, 604/263, 604/207, 604/208, 604/210, 604/212, 604/197, 604/192, 604/187, 206/364, 206/365, 206/367
• US Class Current: 604/110
• CPC Class Codes: A61M 5/282 by compression of deformable ampoule or carpule wall
• CPC Class Codes: A61M 5/31505 Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/5066 Means for preventing re-use by disconnection of piston and piston-rod

Abstract

A simple mechanism that provides the manipulations required to deliver a correct injection and also incorporates the safety modifications that are needed to prevent needlestick injury and ensure self destruct capability. A surprisingly simple and cheap modification to a sterile package for the standard syringe and needle can successfully be used to automate the medical skills needed to deliver a safe injection and dispose of the hazardous needle afterwards. The sterile package consists of a housing for the syringe barrel, which can telescope into a larger diameter hollow cap covering the syringe plunger. The syringe and needle are located fully inside this two-part packaging sheath, which completely encloses and protects them.

Claims

1. A single use injector device for dispensing medication from a pre-filled syringe and sealing the syringe in the device after use, the pre-filled syringe including a barrel open with a flange at one end and having a needle mounted in a hub at an opposite end, a plunger slidably mounted in the barrel having a stopper at one end engaging a predetermined dose of a drug and a flange at an opposite end, the single use injector device comprising:

a housing,

a spring located in a lumen of the housing for engaging the hub of the barrel of the syringe,

a cap slidably mounted on the housing for progressively moving along a longitudinal axis of the housing while the needle of the syringe is moved from an interior of the housing to an exterior of the housing and delivery of the predetermined dose of the drug and retraction of the needle into the housing after use to prevent exposure to the used needle, and

one end of said housing being sealed with an adherent foil having a pull-tab for removal of the foil and leaving an exposed adhesive surface at the one end of the housing.

2. A single use injector device for dispensing medication from a pre-filled syringe and sealing the syringe in the device after use, the pre-filled syringe including a barrel open with a flange at one end and having a needle mounted in a hub at an opposite end, a plunger slidably mounted in the barrel having a stopper at one end engaging a predetermined dose of a drug and a flange at an opposite end, the single use injector device comprising:

a housing,

a spring located in a lumen of the housing for engaging the hub of the barrel of the syringe, and

a cap slidably mounted on the housing for progressively moving along a longitudinal axis of the housing while the needle of the syringe is moved from an interior of the housing to an exterior of the housing and delivery of the predetermined dose of the drug and retraction of the needle into the housing after use to prevent exposure to the used needle,

said cap including three sets of break tabs, a first set of said three sets of break tabs engaging one end of the housing prior to movement of the syringe in the housing, a second set of said three sets of break tabs engaging the flange of the barrel of the syringe after the first set of break tabs is broken by movement of the cap, a third set of said three sets of break tabs engaging the flange of the plunger of the syringe after the first set and the second set of break tabs are broken, the third set of said three sets of break tabs being broken upon movement of the cap along the barrel after breaking of the first and second sets of break tabs,

the first set of break tabs projecting into the interior of the cap less than the second and third sets of break tabs and the second set of break tabs projecting into the interior of the cap less than the third set of break tabs.

3. The single use injector device as claimed in claim 2, wherein the spring retracts the needle into the housing and moves the plunger and the barrel of the syringe up into the cap after the third set of break tabs is broken.

4. The single use injector device as claimed in claim 3, wherein a locking ring of the cap engages a locking ring of the housing to lock the cap and housing together after extension and retraction of the needle from the housing to prevent exposure to the used needle.

5. A single use injector comprising:

a container for medication;

an expulsion device for expelling the medication from the container;

a needle for delivering the expelled medication through the skin of a patient;

an operating mechanism designed to apply hand pressure to push the needle through the skin and to operate the expulsion device;

a spring-action mechanism to withdraw the needle into the operation mechanism after use; and

a detent releasing in response to hand pressure greater than a predetermined value so that the operating mechanism is caused to operate in two stages;

a) a first stage, before release of the detent, in which the application of pressure pushes the needle through the skin, and

b) a second stage, after release of the detent, in which continued application of pressure operates the expulsion device.

6. The injector according to claim 5, further comprising a final detent which releases in response to the hand pressure greater than a second predetermined value, greater than the first predetermined value, to release the spring-action mechanism so that the needle is withdrawn.

7. The injector according to claim 6, further comprising an initial detent which releases in response to hand pressure being greater than an initial value thereby allowing the needle to be pushed through the skin of the patient.

8. The injector according to claim 7, wherein the operating mechanism includes a housing which encloses the needle before the initial detent is released and after the final detent is released.

9. The injector according to claim 8, wherein the container includes a barrel and a plunger slides in the barrel to expel the medication, the detent acting directly between the barrel and the operating mechanism to push the needle through the skin of the patient, and the operating mechanism is effective, after release of the detent, to operate the plunger to expel the medication.

10. A single use injector device for dispensing medication from a pre-filled syringe and sealing the syringe in the device after use, the pre-filled syringe including a blister having a predetermined dose of a drug, a hollow hub, a collar and a needle mounted on the collar, the single use injector comprising:

a shaped moulding for engaging the blister,

a barrel,

a spring located in the barrel, and

a cap slidably mounted on the barrel progressively moving along a longitudinal axis of the barrel while the needle of the syringe is moved from an interior of the barrel to an exterior of the barrel and delivery of the predetermined dose of the drug and retraction of the needle into the barrel after use to prevent exposure to the used needle.

11. The single use injector device as claimed in claim 10, wherein movement of the cap with respect to the barrel causes one end of the needle to puncture a patient'"'"'s skin and an opposite end of the needle punctures the blister containing the drug by extension of the needle through the hollow hub.

12. The single use injector device as claimed in claim 10, wherein one end of said barrel is sealed with an adherent foil having a pull-tab for removal of the foil and leaving an exposed adhesive surface at the one end of the barrel.

13. The single use injector device as claimed in claim 10, wherein said cap includes two sets of break tabs.

14. The single use injector device as claimed in claim 13, wherein a first set of said two sets of break tabs engages one end of said barrel prior to movement of the syringe in the barrel.

15. The single use injector device as claimed in claim 14, wherein a second set of said two sets of break tabs engages an end of said syringe opposite to the needle and moves a dome shaped area of the shaped moulding to squeeze said blister after breakage of the first set of break tabs.

16. The single use injector device as claimed in claim 15, wherein continued movement of the cap with respect to the barrel after breakage of the first set of tabs causes breakage of the second set of tabs and movement of the syringe into the cap and retraction of the needle by a bias force of the spring.

17. The single use injector device as claimed in claim 10, wherein the moulding includes two curved extensions.

18. The single use injector device as claimed in claim 17, wherein the curved extensions each include a grooved defect.

19. The single use injector device as claimed in claim 11, wherein the moulding is folded in half.