Implant made of a reabsorbable ceramic material

• US 6,811,570 B1
• Filed: 11/30/2001
• Issued: 11/02/2004
• Est. Priority Date: 10/21/1997
• Status: Expired due to Fees

• Current Assignee: Augmentec AG
• Original Assignee: Augmentec AG
• Inventors: Gehl, Gerolf
• Primary Examiner(s): Isabella, David J.
• Application Number:
  US09/529,897
• Time in Patent Office: 1,068 Days
• Field of Search: 623/8, 623/11.11, 623/16.11, 623/23.56, 623/23.57, 623/23.58, 623/23.6, 623/23.61, 623/23.64, 623/23.72, 623/23.73, 623/23.74, 623/23.75, 435/284, 435/240, 424/422, 424/423, 424/424, 423/305, 423/306, 423/307
• US Class Current: 623/23.75
• CPC Class Codes: A61F 2/02 Prostheses implantable into the body closure means for urethra or rectum or for artificial body openings therefor A61F2/0004
• CPC Class Codes: A61F 2/12 Mammary prostheses and implants
• CPC Class Codes: A61L 2430/04 for mammary reconstruction
• CPC Class Codes: A61L 27/10 Ceramics or glasses
• CPC Class Codes: A61L 27/12 Phosphorus-containing materials, e.g. apatite
• CPC Class Codes: A61L 27/28 Materials for coating prostheses
• CPC Class Codes: A61L 27/34 Macromolecular materials
• CPC Class Codes: A61L 27/38 containing added animal cells organs or tissue containing native cells A61L27/36
• CPC Class Codes: A61L 27/3804 characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
• CPC Class Codes: A61L 27/3813 Epithelial cells, e.g. keratinocytes, urothelial cells
• CPC Class Codes: A61L 27/3839 characterised by the site of application in the body materials for artificial blood vessels A61L27/507; materials for use in artificial skin A61L27/60
• CPC Class Codes: A61L 27/3895 using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body
• CPC Class Codes: C03C 11/00 Multi-cellular glass ; Porous or hollow glass or glass particles
• CPC Class Codes: C03C 12/00 Powdered glass C03C8/02 takes precedence; Bead compositions
• CPC Class Codes: C03C 4/0007 for biologically-compatible glass
• CPC Class Codes: C08L 89/00 Compositions of proteins; Compositions of derivatives thereof foodstuff preparations A23J3/00
• CPC Class Codes: C08L 89/06 derived from leather or skin , e.g. gelatin

Abstract

The invention relates to an implant, especially a breast implant, which is made of a biocompatible material with a pore structure. The biocompatible material is preferably designed to be reabsorbable.

Claims

1. An implant for adding or restoring a human soft tissue, comprising a shell and a core covered by the shell, the core and the shell being made of a soft tissue-compatible glass ceramic material with a porous structure formed to facilitate vascularization and ingrowth of the human soft tissue, said material consisting of sintered phosphate glass granules with a grain size of 200-500 μ

m and being resorbable by a body, wherein the core is formed to be resorbed faster than the shell by the body.

2. The implant according to claim 1, wherein the implant is pre-shaped in a form of a body part.

3. The implant according to claim 1, further comprising a coating of keratinocytes, collagen or a material which promotes collagen formation on body cells.

4. The implant according to claim 3, wherein the coating is composed of a natural or a synthetic peptide.

5. The implant according to claim 1, wherein the glass ceramic material is set to a pH value between 7.7 and 8.7.

6. The implant as claimed in claim 5, wherein the implant is preshaped and modifiable and adaptable by removing a portion of the glass ceramic material therefrom.

7. The implant as claimed in claim 6, wherein the implant is impregnated with viable cells.

8. The implant as claimed in claim 7, wherein the implant is precultivated in a cell-containing nutrient solution.

9. The implant as claimed in claim 1, wherein the implant is used for the restoration or enlargement of a breast.