Method for the purification of blood by means of hemodialysis and/or hemofiltration and apparatus for performing said method
First Claim
1. A method for blood purification by means of hemodialysis and/or hemofiltration using a hemodialysis and/or hemofiltration device having an extra-corporeal blood circuit in communication with a hemodialyser and/or hemofilter that is divided by a membrane, said blood circuit having an upstream supply line and a downstream supply line upstream and downstream, respectively, of said hemodialyser and/or hemofilter for supplying a substitution fluid, said hemodialysis and/or hemofiltration device further including a control unit connected to a measurement device, the method comprising the steps of:
- receiving in said extra-corporeal blood circuit blood to be purified;
measuring by said measurement device at least one operational and/or blood parameter within the received blood, said operational and/or blood parameter being selected from the group consisting of trans-membrane pressure, hematocrit value and blood density;
controlling, by said control unit, at least one of an infusion rate (Qspre) of said upstream supply line and an infusion rate (Qspost) of said downstream supply line, in response to said step of measuring in order to control said at least one operational and/or blood parameter.
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Accused Products
Abstract
The present invention refers to a method for blood purification by means of hemodialysis and/or hemofiltration, wherein to the blood in the extra-corporeal circuit of the hemodialysis and/or hemofiltration device a substitution solution is added upstream as well as downstream of the hemodialyser and/or hemofilter. A purification effect remaining constant with a high purification performance is achieved in that one or several of the operational and/or blood parameters are controlled and that the control is carried out using at least one of the infusion rates of the substitution solutions supplied upstream or downstream of the hemodialyser and/or hemofilter. The present invention also refers to a hemodialysis and/or hemofiltration apparatus for the performance of the inventive method.
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Citations
13 Claims
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1. A method for blood purification by means of hemodialysis and/or hemofiltration using a hemodialysis and/or hemofiltration device having an extra-corporeal blood circuit in communication with a hemodialyser and/or hemofilter that is divided by a membrane, said blood circuit having an upstream supply line and a downstream supply line upstream and downstream, respectively, of said hemodialyser and/or hemofilter for supplying a substitution fluid, said hemodialysis and/or hemofiltration device further including a control unit connected to a measurement device, the method comprising the steps of:
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receiving in said extra-corporeal blood circuit blood to be purified;
measuring by said measurement device at least one operational and/or blood parameter within the received blood, said operational and/or blood parameter being selected from the group consisting of trans-membrane pressure, hematocrit value and blood density;
controlling, by said control unit, at least one of an infusion rate (Qspre) of said upstream supply line and an infusion rate (Qspost) of said downstream supply line, in response to said step of measuring in order to control said at least one operational and/or blood parameter. - View Dependent Claims (2, 3, 4, 5)
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6. A hemodialysis and/or hemofiltration apparatus comprising:
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an extra-corporeal blood circuit for receiving blood to be purified;
a hemodialyser and/or hemofilter communicating with said blood circuit;
said blood circuit having an upstream supply line and a downstream supply line upstream and downstream, respectively, of said hemodialyser and/or hemofilter for supplying a substitution fluid, said upstream supply line having an upstream infusion rate (Qspre) and said downstream supply line having a downstream infusion rate (Qspost);
a measuring device including at least one sensor for recording at least one operational and/or blood parameter selected from the group consisting of trans-membrane pressure, hematocrit value and blood density; and
a control unit connected to said measuring device for controlling said at least one operational and/or blood parameter by controlling at least one of said upstream and downstream infusion rates in response to data received from said measuring device. - View Dependent Claims (7, 8, 9, 10, 11)
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12. A method for blood purification by means of hemodialysis and/or hemofiltration using a hemodialysis and/or hemofiltration device having an extra-corporeal blood circuit in communication with a hemodialyser and/or hemofilter that is divided by a membrane, said blood circuit having an upstream supply line and a downstream supply line upstream and downstream, respectively, of said hemodialyser and/or hemofilter for supplying a substitution fluid, said hemodialysis and/or hemofiltration device further including a control unit connected to a measurement device, the method comprising the steps of:
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receiving in said extra-corporeal blood circuit blood to be purified;
measuring by said measurement device at least one operational and/or blood parameter of the received blood;
controlling, by said control unit, at least one of an infusion rate (Qspre) of said upstream supply line and an infusion rate (Qspost) of said downstream supply line, in response to said step of measuring in order to control said at least one operational and/or blood parameter; and
selecting said infusion rates (Qspre, Qspost) such that a substantially stationary limiting membrane is formed on a side of the membrane of the hemodialyser and/or hemofilter facing a chamber through which the blood flows. - View Dependent Claims (13)
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Specification