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Efficient compound distribution in microfluidic devices

  • US 6,824,663 B1
  • Filed: 08/25/2000
  • Issued: 11/30/2004
  • Est. Priority Date: 08/27/1999
  • Status: Expired due to Term
First Claim
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1. A microfluidic device formed from a substrate, said device comprising a plurality of individual units in said substrate, each individual unit comprising 4 subunits, where the 4 subunits have 4-fold symmetry, said units further characterized by:

  • a common supply reservoir containing a target compound for said 4 subunits; and

    each subunit comprising;

    a compound reservoir containing a test compound;

    a delivery channel connecting with both the common supply reservoir and the compound reservoir such that the test compound and the target compound form an assay mixture when such test compound and target compound are transported through the delivery channel;

    an assay channel connecting a buffer reservoir and a waste reservoir and crossing the delivery channel to form a cross-intersection for injecting the assay mixture from the delivery channel into the assay channel, the assay mixture being transported along the assay channel toward the waste reservoir for detection.

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