Stabilization of implantable bioprosthetic tissue
First Claim
Patent Images
1. A method of manufacturing an implantable bioprosthesis, the method comprising:
- providing the bioprosthesis comprising proteins;
providing a first stabilizing reagent which is a polyepoxy amine compound; and
contacting the bioprosthesis and the polyepoxy amine compound, whereby the bioprosthesis is manufactured.
0 Assignments
0 Petitions
Accused Products
Abstract
The invention relates to implantable bioprostheses (e.g. implantable biological tissues) and to compositions and methods for stabilizing them. Implantable bioprostheses stabilized as described herein exhibit improved mechanical properties and reduced post-implantation calcification. The implantable bioprosthesis is made by contacting a bioprosthesis (e.g. a tissue obtained from an animal or an article comprising a tissue and a synthetic material) with a polyepoxy amine compound.
-
Citations
13 Claims
-
1. A method of manufacturing an implantable bioprosthesis, the method comprising:
-
providing the bioprosthesis comprising proteins;
providing a first stabilizing reagent which is a polyepoxy amine compound; and
contacting the bioprosthesis and the polyepoxy amine compound, whereby the bioprosthesis is manufactured. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
-
Specification