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Depth-resolved fluorescence instrument

  • US 6,825,928 B2
  • Filed: 12/18/2002
  • Issued: 11/30/2004
  • Est. Priority Date: 12/19/2001
  • Status: Expired due to Term
First Claim
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1. A fluorescence instrument which comprises:

  • a light source for producing light;

    illumination optical fiber for conveying the light to the surface of a subject to be examined and having an end disposed to direct light at a first location on said surface;

    a collection optical fiber for collecting light emanating from the surface of the subject which is produced by fluorescence within the subject and beneath the surface, the optical fiber having an end disposed to receive light from a second location on said surface; and

    ;

    means for changing the effective aperture of the fluorescence instrument to enable fluorescence measurements of the subject to be made at different depths beneath the surface; and

    in which the means for changing includes means for changing the second location by moving the collection optical fiber to different positions relative to the illumination optical fiber.

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