Signal processing apparatus and method

• US 6,826,419 B2
• Filed: 12/20/2002
• Issued: 11/30/2004
• Est. Priority Date: 03/07/1991
• Status: Expired due to Fees

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Diab, Mohamed Kheir, Kiani-Azarbayjany, Esmaiel
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US10/327,234
• Publication Number:
  US 20030097049A1
• Time in Patent Office: 711 Days
• Field of Search: 600/310, 600/322, 600/323, 600/330, 600/336
• US Class Current: 600/336
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7214 using signal cancellation, e.g. based on input of two identical physiological sensors spaced apart, or based on two signals derived from the same sensor, for different optical wavelengths
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: G06F 2218/04 Denoising
• CPC Class Codes: H04B 1/123 using adaptive balancing or compensation means adaptive filter circuits and algorithms H03H

Abstract

A signal processor which acquires a first signal, including a first desired signal portion and a first undesired signal portion, and a second signal, including a second desired signal portion and a second undesired signal portion, wherein the first and second desired signal portions are correlated. The signals may be acquired by propagating energy through a medium and measuring an attenuated signal after transmission or reflection. Alternatively, the signals may be acquired by measuring energy generated by the medium. A processor of the present invention generates a noise reference signal that is a combination of the undesired signal portions and is correlated to both the first and second undesired signal portions. The noise reference signal is then used to remove the undesired portion of each of the first and second measured signals. The processor of the present invention may be employed in physiological monitors wherein the known properties of energy attenuation through a medium are used to determine physiological characteristics of the medium. Many physiological conditions, such as the pulse of a patient or the concentration of a constituent in a medium, can be determined from the desired portion of the signal after undesired signal portions, such as those caused by erratic motion, are removed.

Claims

1. A method for physiological monitoring, comprising:

acquiring a first signal comprising a first desired signal component and a first noise component and a second signal comprising a second desired signal component and a second noise component;

transforming said first and second signals to produce transformed signals wherein at least the first and second desired signal components and the first and second noise components are combined by addition; and

removing at least a substantial portion of motion-induced noise from the transformed signals.

2. The method of claim 1 wherein said removing comprises an additive relationship.

3. The method of claim 2 wherein said removing further comprises an adaptive algorithm.

4. A pulse oximeter comprising:

at least first and second light emitting devices;

at least one light detector configured to receive light attenuated by transmission through body tissue with pulsing blood, the at least one light detector generating a first signal based on light transmitted from the first light emitting device, and a second signal based on light transmitted from the second light emitting device;

a signal transformer for transforming at least said first signal to produce a first transformed signal wherein a first desired signal component and a first noise component of said first transformed signal are combined by addition; and

at least one processor that processes at least the first transformed desired signal component and first noise component to produce an output signal that approximates the first desired signal component and a second desired signal component, and which computes oxygen saturation, wherein the at least one processor comprises a least squares algorithm.

5. A pulse oximeter comprising:

at least first and second light emitting devices;

at least one light detector configured to receive light attenuated by transmission through body tissue with pulsing blood, the at least one light detector generating a first signal based on light transmitted from the first light emitting device, and a second signal based on light transmitted from the second light emitting device;

a signal transformer for transforming at least said first signal to produce a first transformed signal wherein a first desired signal component and a first noise component of said first transformed signal are combined by addition; and

at least one processor that processes at least the first transformed desired signal component and first noise component to produce an output signal that approximates the first desired signal component and a second desired signal component, and which computes oxygen saturation, wherein the at least one processor comprises an adaptive noise canceller.

6. A pulse oximeter comprising:

at least first and second light emitting devices;

at least one light detector configured to receive light attenuated by transmission through body tissue with pulsing blood, the at least one light detector generating a first signal based on light transmitted from the first light emitting device, and a second signal based on light transmitted from the second light emitting device;

a signal transformer for transforming at least said first signal to produce a first transformed signal wherein a first desired signal component and a first noise component of said first transformed signal are combined by addition; and

at least one processor that processes at least the first transformed desired signal component and first noise component to produce an output signal that approximates the first desired signal component and a second desired signal component, and which computes oxygen saturation, wherein the at least one processor comprises a least squares lattice.

7. The pulse oximeter of claim 6, further comprising a display to display the oxygen saturation.

8. A method of calculating blood oxygen saturation comprising:

transmitting light of at least first and second wavelengths through body tissue carrying pulsing blood to a light-sensitive detector to generate first and second intensity signals;

digitizing the first and second intensity signals;

transforming said digitized first and second intensity signals such that a first plurality of components of said digitized first intensity signal are combined by addition and a second plurality of components of said digitized second intensity signal are combined by addition;

processing said first and second plurality of components to provide first and second processed output signals, wherein the processing comprises improving at least one of said first or second processed output signals to reduce undesired components; and

calculating oxygen saturation based upon said first and second processed output signals, wherein said processing comprises executing a least squares algorithm to convergence.

9. A method of calculating blood oxygen saturation comprising:

transmitting light of at least first and second wavelengths through body tissue carrying pulsing blood to a light-sensitive detector to generate first and second intensity signals;

digitizing the first and second intensity signals;

transforming said digitized first and second intensity signals such that a first plurality of components of said digitized first intensity signal are combined by addition and a second plurality of components of said digitized second intensity signal are combined by addition;

processing said first and second plurality of components to provide first and second processed output signals, wherein the processing comprises improving at least one of said first or second processed output signals to reduce undesired components; and

calculating oxygen saturation based upon said first and second processed output signals, wherein said processing comprises executing an error reducing algorithm to convergence.

10. A method of calculating blood oxygen saturation comprising:

transmitting light of at least first and second wavelengths through body tissue carrying pulsing blood to a light-sensitive detector to generate first and second intensity signals;

digitizing the first and second intensity signals;

transforming said digitized first and second intensity signals such that a first plurality of components of said digitized first intensity signals are combined by addition and a second plurality of components of said digitized second intensity signals are combined by addition;

processing said first and second plurality of components to provide first and second processed output signals, wherein the processing comprises improving at least one of said first or second processed output signals to reduce undesired components; and

calculating oxygen saturation based upon said first and second processed output signals, wherein said processing comprises executing a least squares lattice.

11. The method of claim 10, wherein the least squares lattice is a component of an adaptive noise canceller.

12. A method of determining blood oxygen saturation comprising:

transmitting light of at least first and second wavelengths through body tissue carrying pulsing blood to a light-sensitive detector to generate at least one intensity signal; and

calculating oxygen saturation at least in part by using a recursive algorithm to remove at least a portion of a noise component of said at least one intensity signal based upon a principle that the oxygen saturation changes relatively slowly over short periods of time.

13. The method of claim 12 wherein the calculation occurs during the presence of motion-induced noise in the intensity signal.

14. A method for removing unwanted signal components in a pulse oximeter, comprising:

receiving a first signal corresponding to light of a first wavelength band attenuated by transmission through body tissue with pulsing blood, and receiving a second signal corresponding to light of a second wavelength band attenuated by transmission through said pulsing blood, said first signal comprising a first desired portion in combination with a first undesired portion;

using a recursive algorithm to obtain an estimate of said first desired signal portion; and

computing a physiological parameter using at least said estimate of said first desired signal portion and at least a portion of said second signal.

15. The method of claim 14, wherein said recursive algorithm comprises an adaptive filter.

16. The method of claim 14, wherein said recursive algorithm comprises a least squares algorithm.

17. The method of claim 14, wherein said first desired portion in combination with a first undesired portion comprises an additive combination.

18. A method for removing unwanted signal components in a pulse oximeter, comprising:

receiving a first signal corresponding to an intensity of light of a first wavelength band attenuated by transmission through body tissue with pulsing blood, and receiving a second signal corresponding to an intensity of light of a second wavelength band attenuated by transmission through said pulsing blood, said first signal comprising a first desired portion in combination with a first undesired portion;

using a recursive algorithm to obtain an estimate of said first desired signal portion; and

computing a physiological parameter using at least said estimate of said first desired signal portion and at least a portion of said second signal.

19. The method of claim 18, said recursive algorithm comprises an adaptive filter.

20. The method of claim 18, wherein said recursive algorithm comprises a least squares algorithm.

21. The method of claim 18, wherein said first desired portion in combination with a first undesired portion comprises an additive combination.