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Continuous form microstructure assay array

  • US 6,827,906 B1
  • Filed: 05/09/2000
  • Issued: 12/07/2004
  • Est. Priority Date: 10/15/1997
  • Status: Expired due to Term
First Claim
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1. A continuous form microstructure array for conducting a plurality of assays, the microstructure array comprising:

  • a flexible elongate laminate having a plurality of microstructures arranged therein, the flexible elongate laminate comprising a first lamina having a first surface, a second lamina having a second surface, and a flexible circuit laminate adjacent to the first lamina, wherein at least one of the first or second lamina has a plurality of openings so that whenever the first surface of the first lamina apposes the second surface of the second lamina each opening of the plurality of openings is in fluid communication with one of said plurality of microstructures, and wherein the flexible circuit laminate comprises a plurality of electrodes, each electrode being in contact with an electroflow medium whenever the electroflow medium is supplied to said microstructures, each of said microstructures comprising;

    a sample supply reservoir at an opening;

    a sample drain reservoir connected to the sample supply reservoir by one or more microchannel segments;

    an elution buffer reservoir;

    an analyte waste reservoir; and

    a separation channel connecting the elution buffer reservoir and the analyte waste reservoir and intersecting and being in fluid communication with said one or more microchannel segments; and

    wherein the flexible elongate laminate forms a roll or or an accordion-folded stack.

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