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Nucleic acid affinity columns

  • US 6,828,104 B2
  • Filed: 08/14/2002
  • Issued: 12/07/2004
  • Est. Priority Date: 03/11/1996
  • Status: Expired due to Term
First Claim
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1. A method for eliminating a plurality of preselected gene products from a nucleic acid sample comprising:

  • providing an affinity matrix comprising at least one nucleic acid affinity ligand complementary to each of the plurality of preselected gene products;

    hybridizing the nucleic acid sample to the affinity matrix; and

    eluting the sample from the affinity matrix;

    thereby substantially depleting the nucleic acid sample of the preselected gene products.

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