Active medical device able to diagnose a patient respiratory profile

• US 6,830,548 B2
• Filed: 09/24/2002
• Issued: 12/14/2004
• Est. Priority Date: 09/24/2001
• Status: Expired due to Term

• Current Assignee: Sorin CRM SAS (MicroPort Scientific Corp.)
• Original Assignee: Ela Medical S.A. (LivaNova Plc)
• Inventors: Limousin, Marcel, Bonnet, Jean-Luc
• Primary Examiner(s): Nasser, Robert L.
• Assistant Examiner(s): MALLARI, PATRICIA C
• Application Number:
  US10/255,144
• Publication Number:
  US 20030078619A1
• Time in Patent Office: 812 Days
• Field of Search: 607/28, 607/42, 607/62, 607/63, 607/2-6, 607/9, 607/17-20, 600/529-543, 600/50.B, 600/547, 600/508, 600/513
• US Class Current: 600/529
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

An active medical device to diagnose a patient respiratory profile. This device is able to measure respiratory activity and deliver a signal (26) representative of the periodicity and amplitude of the successive respiratory cycles of the patient, in particular, a of minute ventilation (MV) signal. The device is able to analyze the aforementioned signal and discriminate between various types of respiratory profiles, in particular, to diagnose a respiratory profile of the Cheyne-Stokes type. This is achieved by detecting an alternation of respiratory cycles of hyperventilation (20) separated by periods of respiratory pause (22) or periods of hypoventilation or normal ventilation (24) and, in the latter case, to discriminate between periods of respiratory pause, corresponding to a profile of the Cheyne-Stokes (CSR) type, and periods of hypoventilation or normal ventilation, corresponding to a profile of the periodic breathing (PB) type.

Claims

1. An active medical device of the pacemaker, defibrillator, cardiovertor and/or multisite device type, comprising:

means for measuring respiratory activity and providing a signal representative of the periodicity and amplitude of a plurality of successive respiratory cycles of a patient,

discriminating means for analyzing the signal, discriminating between various types of respiratory profiles, and diagnosing a Cheyne-Stokes type respiratory profile,

said discriminating means comprising;

means for detecting in said signal an alternation of a hyperventilation respiratory cycle separated by one of a respiratory pause period, a hypoventilation period, and a normal ventilation period, and

second discriminating means, responsive to a detected alternation of a hyperventilation and a normal ventilation, for discriminating between a respiratory pause period and a hypoventilation period or a normal ventilation period by analysis of variation of a second order of said signal, said second discriminating means further comprising means for analyzing the variation of the second order of the signal by identifying a peak value of said signal and an interval between successive peak values.

2. The device of claim 1, wherein the discriminating means further comprises means for comparing the interval between successive peaks to a threshold value, and diagnosing a Cheyne-Stokes type respiratory profile only for said interval having a duration greater than said threshold value.

3. The device of the claim 1, wherein the discriminating means further comprises means for comparing the peak amplitude with a given minimal value and wherein the means for analyzing the variation of the second order of the signal is responsive to seek a peak value in response to the amplitude value of the signal being greater than the given minimal value.

4. The device of the claim 2, further comprising means for determining whether the interval is between a minimal value and a maximum value, wherein the discriminating means comparison is operated only for values of intervals ranging between said minimal and maximum values.

5. The device of claim 1 wherein said provided signal is representative of the patient'"'"'s minute ventilation.