Method and device for non-invasive regulation of temperature with radiation, especially laser radiation of biological tissue
First Claim
1. Method for non-invasive determination of temperature on biological tissue, including the fundus of an eye, treated by radiation, comprisingduring a respective irradiation period by the treatment radiation, aiming additional radiation, which have pulses of a shorter pulse duration and a lower energy than those pulses generated during the treatment radiation at the biological tissue, or switching off the treatment radiation for a short time and switching the treatment radiation back on, detecting resulting at least one of tissue expansions and contractions by one of a pressure or an optical measurement, and from a signal from the measurement, determining at least one of temperature and the temperature rise.
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Abstract
A method and a system for the non-invasive temperature determination on biological tissue, particularly at the fundus of the eye, treated by a treatment radiation, particularly laser radiation, wherein, during the respective irradiation time, at essentially identical time intervals, additional radiation pulses of a shorter pulse duration and a lower energy are aimed at the treated biological tissue, the resulting tissue expansions and/or contractions being detected by a pressure measurement or optical measurement and, from the measuring signals, the absolute temperature values are determined and optionally the treatment radiation is controlled as a function thereof.
32 Citations
17 Claims
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1. Method for non-invasive determination of temperature on biological tissue, including the fundus of an eye, treated by radiation, comprising
during a respective irradiation period by the treatment radiation, aiming additional radiation, which have pulses of a shorter pulse duration and a lower energy than those pulses generated during the treatment radiation at the biological tissue, or switching off the treatment radiation for a short time and switching the treatment radiation back on, detecting resulting at least one of tissue expansions and contractions by one of a pressure or an optical measurement, and from a signal from the measurement, determining at least one of temperature and the temperature rise.
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9. System for non-invasive determination of temperature of biological tissue which is treated by radiation, including laser radiation, with a defined treatment time, comprising
a treatment radiation source for generating the treatment radiation, a control device configured to control the treatment radiation source during the defined treatment time, an irradiation lens system for aiming the treatment radiation at the biological tissue, an additional radiation source which, during the treatment time, is coupleable into the irradiation lens system for supplying additional radiation pulses, a detector for measuring by at least one of acoustically and optically at least one of expansions and contractions caused by the radiation, and an analyzing device which has a calibration curve indicating proportionality of the at least one of acoustically and optically detected measuring signals to the temperature and so as to convert the detected measurement into a temperature value.
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17. System for non-invasive temperature determination of biological tissue which is treated by radiation, including laser radiation with a defined treatment time, comprising
a treatment radiation source for generating the treatment radiation, a control device configured to control the treatment radiation source during the defined treatment time, an irradiation lens system for aiming the treatment radiation at the biological tissue, a switching device operatively controlled by the control device during the respectively defined irradiation time, to switch the treatment radiation source off for a short duration and then back on, a detector for measuring at least one of acoustically and optically at least one of expansions and contractions caused by the radiation, and an analyzing device which has a calibration curve indicating proportionality of the at least one of the acoustically and optically detected measurements to temperature so as to convert the measurement signal into a temperature value.
Specification