Devices and methods for preventing distal embolization using flow reversal and perfusion augmentation within the cerebral vasculature

• US 6,830,579 B2
• Filed: 05/02/2001
• Issued: 12/14/2004
• Est. Priority Date: 05/01/2001
• Status: Expired due to Fees

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Coaxis Incorporated (Trimble Inc.)
• Inventors: Barbut, Denise R.
• Primary Examiner(s): Reip, David O.
• Assistant Examiner(s): Baxter, Jessica R.
• Application Number:
  US09/847,425
• Publication Number:
  US 20020165573A1
• Time in Patent Office: 1,322 Days
• Field of Search: 606/200, 606/144, 606/113, 606/114, 606/159, 604/101.01, 604/101.05
• US Class Current: 606/200
• CPC Class Codes: A61F 2/014 Retrograde blood flow filters, i.e. device inserted against the blood flow direction
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61M 2025/1015 having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

A medical device having a catheter and one or more expandable constricting/occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty/stent catheter and an atherectomy catheter. A first constrictor/occluder mounted at the distal end of the catheter is adapted for placement in a brachiocephalic or subclavian artery. A second constrictor mounted proximal to the first constrictor/occluder is adapted for placement in the descending aorta. Pressure measuring devices may be included, and filters may be used to capture embolic debris. Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by augmenting collateral cerebral circulation by coarctation of the aorta to enhance reversal of blood flow in an internal carotid artery, an external carotid artery, and/or a common carotid artery toward the subclavian artery are disclosed.

Claims

1. A method for reversing blood flow in a cerebral artery, comprising the steps of:

locating a first constricting member in the right brachiocephalic artery upstream of the right common carotid artery;

locating a second constricting member in the aorta downstream of the left common carotid artery;

expanding the first constricting member to at least partially obstruct the right brachiocephalic artery; and

expanding the second constricting member to at least partially obstruct the aorta, wherein flow in the right common carotid artery is reversed to pass into the subclavian artery.

2. The method of claim 1, wherein blood flow is reversed in the right internal carotid artery.

3. The method of claim 1, further comprising the steps of advancing an interventional catheter into a right cerebral artery and performing a procedure on a lesion in the right cerebral artery.

4. The method of claim 3, wherein the right cerebral artery is selected from the group consisting of the right common carotid artery, right internal carotid artery, right external carotid artery, right vertebral artery, carotid siphon, MCA, and ACA.

5. The method of claim 3, wherein the interventional catheter is an angioplasty catheter.

6. The method of claim 3, wherein the interventional catheter is an atherectomy catheter.

7. The method of claim 3, wherein the interventional catheter is a stent delivery catheter.

8. The method of claim 1, further comprising the step of deploying a filter in the right subclavian artery to capture embolic debris.