Edge compression manifold apparatus
First Claim
1. A fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate having a network of microchannels, said fluid connector comprising:
- a manifold comprising one or more channels extending therethrough wherein each channel is at least partially threaded and each channel has a tapered configuration;
one or more externally threaded ferrules each defining a bore extending therethrough with each ferrule supporting a fluid conduit wherein each ferrule is threaded into a channel of the manifold and wherein each ferrule defines a lower tapered exterior end;
a substrate having one or more ports on its upper surface wherein the substrate is positioned below the manifold so that the one or more ports is aligned with the one or more channels of the manifold; and
means for applying an axial compressive force to the substrate to couple the one or more ports of the substrate to a corresponding proximal end of a fluid conduit; and
a base plate that is rigidly fastened to and spaced apart from manifold and which is positioned below the substrate; and
a pressure plate that is interposed between the substrate and the base plate.
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0 Petitions
Accused Products
Abstract
A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i) a manifold comprising one or more channels extending therethrough wherein each channel is at least partially threaded, (ii) one or more threaded ferrules each defining a bore extending therethrough with each ferrule supporting a fluid conduit wherein each ferrule is threaded into a channel of the manifold, (iii) a substrate having one or more ports on its upper surface wherein the substrate is positioned below the manifold so that the one or more ports is aligned with the one or more channels of the manifold, and (iv) device to apply an axial compressive force to the substrate to couple the one or more ports of the substrate to a corresponding proximal end of a fluid conduit.
140 Citations
20 Claims
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1. A fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate having a network of microchannels, said fluid connector comprising:
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a manifold comprising one or more channels extending therethrough wherein each channel is at least partially threaded and each channel has a tapered configuration;
one or more externally threaded ferrules each defining a bore extending therethrough with each ferrule supporting a fluid conduit wherein each ferrule is threaded into a channel of the manifold and wherein each ferrule defines a lower tapered exterior end;
a substrate having one or more ports on its upper surface wherein the substrate is positioned below the manifold so that the one or more ports is aligned with the one or more channels of the manifold; and
means for applying an axial compressive force to the substrate to couple the one or more ports of the substrate to a corresponding proximal end of a fluid conduit; and
a base plate that is rigidly fastened to and spaced apart from manifold and which is positioned below the substrate; and
a pressure plate that is interposed between the substrate and the base plate.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification