Method for adaptive triggering of a breathing device, and breathing device with adaptive triggering

• US 6,837,241 B2
• Filed: 10/18/2001
• Issued: 01/04/2005
• Est. Priority Date: 11/13/2000
• Status: Expired due to Term

• Current Assignee: Maquet Critical Care AB (Getinge AB)
• Original Assignee: Maquet Critical Care AB (Getinge AB)
• Inventors: Samzelius, Roger
• Primary Examiner(s): Bennett, Henry
• Assistant Examiner(s): MITCHELL, TEENA KAY
• Application Number:
  US09/982,700
• Publication Number:
  US 20020056454A1
• Time in Patent Office: 1,174 Days
• Field of Search: 128/200.24, 128/204.18, 128/204.21, 128/204.22, 128/204.23, 128/202.16, 128/207.14, 128/207.15, 607/2, 607/3, 607/20, 607/42, 607/212
• US Class Current: 128/204.21
• CPC Class Codes: A61M 16/0063 Compressors
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/60 Muscle strain, i.e. measured on the user
• CPC Class Codes: A61M 2230/65 Impedance, e.g. conductivity, capacity

Abstract

In a method for adaptive triggering of respiratory phases in a breathing device, and a breathing device operating according to the method, first respiration indicator signal is determined based on at least one of the parameters flow and pressure, the respiration indicator signal is compared with a trigger requirement and a trigger signal is generated when the respiration indicator signal fulfils the trigger requirement. In order to shorten response times to respiration changes without losing stability, an excitable cell signal related to respiration is measured, and a second respiration indicator signal is determined based on the measured excitable cell signal, and the trigger requirement is adapted in relation to the second respiration indicator signal.

Claims

1. A method for adaptively triggering respiration phases in a breathing device, comprising the steps of:

providing exclusively pneumatic breathing assistance to a patient via a tubing system connected to a breathing circuit in which the patient participates;

determining a first respiration indicator signal in said breathing gas circuit based on at least one parameter selected from the group consisting of flow and pressure in said breathing gas circuit;

comparing said first respiration indicator signal with a trigger requirement in said exclusively pneumatic breathing assistance;

generating a trigger signal to trigger a respiratory phase in said exclusively pneumatic breathing assistance when said first respiration indicator signal satisfies said trigger requirement;

measuring an excitable cell signal related to respiration in said patient participating in said breathing gas circuit;

determining a second respiration indicator signal based on the measured excitable cell signal; and

adapting said trigger requirement dependent on said second respiration indicator signal.

2. A method as claimed in claim 1 wherein said trigger requirement is trigger sensitivity, and wherein the step of adapting said trigger requirement comprises increasing said trigger sensitivity relative to said first respiration indicator signal when said second respiration indicator signal indicates commencement of a natural change of respiratory phase.

3. A method as claimed in claim 1 wherein said trigger requirement is trigger enablement, and wherein the step of adapting the trigger requirement comprises enabling triggering only when said second respiration indicator signal indicates commencement of a natural change of respiratory phase.

4. A method as claimed in claim 1 wherein the step of measuring an excitable cell signal comprises measuring a phrenic efferent discharge.

5. A method as claimed in claim 1 wherein the step of measuring an excitable cell signal comprises measuring a muscle signal.

6. A method as claimed in claim 5 wherein the step of measuring a muscle cell signal comprises measuring a diaphragm electromyography signal.

7. A method as claimed in claim 1 wherein the step of determining a first respiration indicator signal comprises determining said first respiration signal based on only one of said parameters selected from the group consisting of flow and pressure, and comprising the additional steps of:

determining a third respiration indicator signal based on the other of the parameter selected from the group consisting of flow and pressure; and

additionally adapting said trigger requirement dependent on said third respiration indicator signal.

8. A breathing device comprising:

a tubing system adapted for communication with a subject;

a pneumatic unit in communication with said tubing system for regulating a flow of breathing gas in said tubing system for providing exclusively pneumatic breathing assistance to the subject;

a sensor system in communication with said tubing system including at least one meter selected from the group consisting of a flow meter for measuring flow of said breathing gas in said tubing system and a pressure meter for measuring a pressure of said breathing gas in said tubing system;

a control unit connected to said pneumatic unit for controlling said pneumatic unit, said control unit comprising a first determination unit connected to said sensor system for receiving a measurement signal from said sensor system representing at least one parameter and for determining a first respiration indication signal based on said at least one parameter, a comparator connected to said first determination unit for receiving said first respiration indication signal therefrom and for comparing said first respiration indication signal with a trigger requirement in said exclusively pneumatic breathing assistance, said comparator generating a comparator output dependent on whether said trigger requirement is satisfied by said first respiration indication signal, and a signal generator supplied with said comparator output for generating a trigger signal for controlling triggering of a respiratory phase in said exclusively pneumatic breathing assistance dependent on said comparator output;

an excitable cell detector adapted for detecting excitable cell signals related to respiration by said subject;

a second determination unit supplied with said excitable cell signals for determining a second respiration indicator signal based on said excitable cell signals; and

an adaptation unit supplied with said second respiration indicator and connected to said comparator, for adapting said trigger requirement dependent on said second respiration indicator signal and supplying said trigger requirement to said comparator.

9. A breathing device as claimed in claim 8 wherein said trigger requirement is trigger sensitivity, and wherein said adaptation unit increases the trigger sensitivity relative to said first respiration indicator signal when said second respiration indicator signal indicates commencement of a natural change of respiratory phase.

10. A breathing device as claimed in claim 8 wherein said trigger requirement is trigger enablement, and wherein said adaptation unit adapts said trigger requirement to enable triggering only when said second respiration indicator signal indicates commencement of a natural change of respiratory phase.

11. A breathing device as claimed in claim 8 wherein said excitable cell signal detector comprises a nerve signal sensor.

12. A breathing device as claimed in claim 11 wherein said nerve signal sensor comprises a phrenic efferent signal sensor.

13. A breathing device as claimed in claim 8 wherein said excitable cell signal detector comprises a muscle signal sensor.

14. A breathing device as claimed in claim 13 wherein said muscle signal sensor comprises a diaphragm electromyography sensor.

15. A breathing device as claimed in claim 14 wherein said diaphragm electromyography sensor comprises an esophageal catheter having an array of sensing electrodes.