Lung assist apparatus and methods for use

• US 6,837,906 B2
• Filed: 01/02/2004
• Issued: 01/04/2005
• Est. Priority Date: 08/03/2001
• Status: Expired due to Fees

• Current Assignee: Gateway Edi (Cognizant Technology Solutions Corp.)
• Original Assignee: Ensure Medical, Inc. (Cardinal Health, Inc.)
• Inventors: Ginn, Richard S.
• Primary Examiner(s): SNOW, BRUCE EDWARD
• Application Number:
  US10/750,800
• Publication Number:
  US 20040153166A1
• Time in Patent Office: 368 Days
• Field of Search: 623/23.65, 623/23.64, 623/1.13, 623/1.15, 623/2.12, 623/2.18, 623/9
• US Class Current: 623/23.65
• CPC Class Codes: A61F 2/00 Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents as cosmetic articles, see the relevant subclasses, e.g. wigs, hair pieces, A41G3/00, A41G5/00; artificial nails A45D31/00; dental prostheses A61C13/00; materials for prostheses A61L27/00; artificial hearts A61M60/00; artificial kidneys A61M1/14
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2/2476 Valves implantable in the body not otherwise provided for
• CPC Class Codes: A61F 2/852 Two or more distinct overlapping stents
• CPC Class Codes: A61F 2002/043 Bronchi
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/821 Ostial stents
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61M 16/0406 implanted flow modifiers

Abstract

A lung-assist apparatus includes a tubular housing, a tubular nozzle therein, and a first valve disposed between the housing and nozzle. The housing is implanted across a bifurcation such that the nozzle extends from a first branch communicating with a healthy region of a lung towards a main passage, and terminates proximate a lateral opening in the housing that is disposed within a second branch communicating with a damaged region of the lung. During inhalation, the first valve opens to allow air flow into the first branch, and closes during exhalation to force air through the nozzle, thereby inducing a vacuum for drawing air from the damaged region. A second valve in the second branch opens during exhalation to draw air from the diseased region, and closes during inhalation to prevent air from being drawn into the damaged region.

Claims

1. An apparatus for implantation at a branch in a lung for assisting exhalation from a region of the lung to be isolated, the branch comprising a main passage, said main passage bifurcating into a first branch communicating with a healthy region of the lung and a second branch communicating with an unhealthy region of the lung to be isolated, the apparatus comprising:

a tubular support structure implantable within the branch, the support structure comprising a first end, a second end, and a lateral opening in the wall of the support structure between said first and second ends;

a tubular member comprising an inlet end, an outlet end defining an inner lumen at least partially within the support structure, such that the tubular member being carried by the support structure such that the inlet end is disposed proximate the first end, and the outlet end is disposed proximate the lateral opening, the tubular member defining an outer lumen between its outer surface and the support structure; and

a first valve disposed across the outer lumen, the first valve configured for permitting flow through the outer lumen towards the inlet end of the tubular member, the first valve also configured for limiting flow through the outer lumen towards the outlet end of the tubular member air passing through the inner lumen from the inlet end to the outlet end, will generate a vacuum in the lateral opening.

2. The apparatus of claim 1, wherein the support structure is expandable between a contracted condition for facilitating insertion into the lung, and an enlarged condition for implantation within the branch.

3. The apparatus of claim 2, wherein the support structure comprises a tubular mesh.

4. The apparatus of claim 3, wherein the housing comprises engagement elements for engaging tissue surrounding the branch.

5. The apparatus of claim 1, wherein the support structure comprises a housing, and wherein the tubular member and the first valve are substantially permanently attached to the housing.

6. The apparatus of claim 1, wherein at least one of the tubular member and the first valve are attached to the support structure.

7. The apparatus of claim 1, further comprising one or more struts extending between the outer surface of the tubular member and the support structure.

8. The apparatus of claim 1, further comprising a second valve for limiting flow into the unhealthy region.

9. The apparatus of claim 8, wherein the second valve is configured to open when a vacuum is generated in the lateral opening to allow air flow into the lateral opening towards the second end of the support structure.

10. The apparatus of claim 9, wherein the second valve is configured to close when a vacuum is absent from the lateral opening, thereby preventing air flow into the unhealthy region.

11. The apparatus of claim 8, wherein the second valve is attached to the support structure proximate the lateral opening.

12. The apparatus of claim 1, wherein the first end of the support structure and the outlet end of the tubular member have a predetermined relative cross-section for generating a predetermined vacuum in the lateral opening when air passes through the inner lumen and out of the outlet end.

13. A lung assist device comprising:

a tubular support structure, said support structure having an opening in the wall thereof,

a tubular element housed in said support structure,

a first valve located in the space between said support structure and said tubular element;

a second valve located in said opening,

said device being adapted to be located in the passageway of a lung.

14. The device of claim 13 wherein said first valve is configured to be closed when said second valve is open and wherein said second valve is configured to close when said first valve is open.

15. The device of claim 14 wherein said opening opens into a third tubular element.

16. The device of claim 15 wherein said second valve is located in said third tubular element.

17. A lung assist device comprising:

a tubular support structure having an opening in the wall thereof,

a venturi tube housed in said support structure, said venturi tube having an aperture in the wall thereof which aperture is proximate said opening, and

a valve controlling the flow through said opening, said valve being configured to permit flow in one direction, but to block flow in the opposite direction.

18. The device of claim 17 wherein said support structure comprises a mesh.

19. The device of claim 17 wherein the opening in the side of the support structure is coupled to a tubular member.

20. The device of claim 19 wherein said valve is attached to the support structure.

21. The device of claim 19 wherein the valve is attached to the tubular member.

22. The device of claim 20 wherein the valve is attached to the tubular member.