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Multiplexed fluorescent detection in microfluidic devices

  • US 6,838,680 B2
  • Filed: 07/23/2002
  • Issued: 01/04/2005
  • Est. Priority Date: 05/12/1999
  • Status: Expired due to Term
First Claim
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1. An optical detection and orientation system for irradiating a fluorescent sample in a detection volume of a microchannel, wherein said microchannel is in a solid substrate, said system comprising:

  • a movable optical train comprising a source of excitation light and an optical element for directing said light at said detection volume;

    a detector for receiving light emanating from said detection volume and transferring said emanating light for analysis; and

    a carrier for moving said optical train and excitation light across the surface of said solid substrate comprising said microchannel in response to changes in light emanating from said detection volume.

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