Electrophysiological cardiac mapping system based on a non-contact non-expandable miniature multi-electrode catheter and method therefor

• US 6,839,588 B1
• Filed: 07/29/1998
• Issued: 01/04/2005
• Est. Priority Date: 07/31/1997
• Status: Expired due to Term

• Current Assignee: Case Western Reserve University
• Original Assignee: Case Western Reserve University
• Inventors: Rudy, Yoram
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US09/463,427
• Time in Patent Office: 2,351 Days
• Field of Search: 607/119, 607/122, 600/508, 600/507, 600/510, 600/523
• US Class Current: 600/523
• CPC Class Codes: A61B 17/22012 in direct contact with, or very close to, the obstruction or concrement for removing obstructions in blood vessels by laser A61B18/245
• CPC Class Codes: A61B 2034/2053 Tracking an applied voltage gradient
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/341 Vectorcardiography [VCG]
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/6855 with a distal curved tip
• CPC Class Codes: A61B 5/6856 with a distal loop
• CPC Class Codes: A61B 5/6857 with a distal pigtail shape
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 6/503 for diagnosis of the heart
• CPC Class Codes: A61B 8/0833 involving detecting or locating foreign bodies or organic structures
• CPC Class Codes: A61B 8/0883 for diagnosis of the heart

Abstract

A system (10) for determining electrical potentials on an endocardial surface of a heart is provided. The system includes a non-contact, non-expandable, miniature, multi-electrode catheter probe (12), a plurality of electrodes (32) disposed on an end portion (30) thereof, means for determining endocardial potentials (14) based on electrical potentials measured by the catheter probe, a matrix of coefficients that is generated based on a geometric relationship between the probe surface, and the endocardial surface. A method is also provided.

Claims

1. A system for determining electrical potentials on an endocardial surface of a heart, the system comprising:

a non-contact catheter probe having a surface and a terminal end portion adapted to be positioned in a cavity of the heart, the terminal end portion being adapted to be conformed into a first elongate shape and at least one second curved shape that includes a spiral shape, wherein the terminal end portion is conformed without expanding the terminal end portion;

a plurality of electrodes disposed on the end portion of the probe, the electrodes being adaptable to measure electrical potentials in the cavity;

imaging means for capturing geometric data on the probe and the endocardial surface;

means for determining a geometric relationship between the probe surface and the endocardial surface based on the geometric data;

means for generating a matrix of coefficients representing the geometric relationship between the probe surface and the endocardial surface; and

,

means for determining endocardial potentials based on catheter probe electrode potentials and the matrix of coefficients.

2. The system as set forth in claim 1 wherein the second curved shape resembles one of a pigtail and a helix.

3. The system as set forth in claim 1 wherein the probe includes means for conforming the terminal end portion of the probe to the first elongate shape while being positioned in the cavity and means for conforming the terminal end portion of the probe into the second curved shape once in the cavity.

4. A system as set forth in claim 1, where the terminal end includes a cylindrical cross-section.

5. A system as set for the in claim 1, where means for determining endocardial potentials include means for reconstructing endocardial potentials throughout the endocardial surface on a beat-by-beat basis.

6. A system according to claim 1, further comprising at least one of:

means for generating electrograms based on the determined endocardial potentials; and

,

means for generating isochrone maps based on the electrograms.

7. A system for determining electrical potentials on an endocardial surface of a heart, the system comprising:

a non-contact catheter probe having a surface and a terminal end portion adapted to be positioned in a cavity of the heart, the terminal end portion being cylindrical in cross-section and adapted to be conformed into a first elongate shape and at least one second curved shape that includes a spiral shape, wherein the terminal end portion is conformed without expanding the terminal end portion;

a plurality of electrodes disposed on the end portion of the probe, the electrodes being adaptable to measure electrical potentials in the cavity;

imaging means for capturing geometric data on the probe and the endocardial surface;

means for determining a geometric relationship between the probe surface and the endocardial surface based on the geometric data;

means for generating a matrix of coefficients representing the geometric relationship between the probe surface and the endocardial surface;

means for determining endocardial potentials based on catheter probe electrode potentials and the matrix of coefficients;

means for generating electrograms based on the determined endocardial potentials; and

,

means for generating isochrone maps based on the electrograms.

8. The system as set forth in claim 7 wherein the second curved shape resembles one of a pigtail and a helix.

9. The system as set forth in claim 7 wherein the probe includes means for conforming the terminal end portion of the probe to the first elongate shape while being positioned in the cavity and means for conforming the terminal end portion of the probe into the second curved shape once in the cavity.

10. A system according to claim 7, further comprising at least one of:

means for generating electrograms based on the determined endocardial potentials; and

,

means for generating isochrone maps based on the electrograms.

11. A system for determining electrical potentials on an endocardial surface of a heart, the system comprising:

a non-contact catheter probe means, having a surface and a terminal end portion, for position in a cavity of the heart, the terminal end portion being cylindrical in cross-section and adapted to be conformed into a first elongate shape and at least one second curved shape that includes a spiral shape, wherein the terminal end portion is conformed without expanding the terminal end portion;

electrode means disposed on the end portion of the probe, for measuring electrical potentials;

imaging means for capturing geometric data on the probe and the endocardial surface;

means for determining a geometric relationship between the surface of the probe means and the endocardial surface based on the geometric data;

means for generating a matrix of coefficients representing the geometric relationship between the surface of the probe means and the endocardial surface;

means for determining endocardial potentials based on catheter probe electrode potentials and the matrix of coefficients;

means for generating electrograms based on the determined endocardial potentials; and

,

means for generating isochrone maps based on the electrograms.

12. A system according to claim 11, further comprising at least one of:

means for generating electrograms based on the determined endocardial potentials; and

,

means for generating isochrone maps based on the electrograms.