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Method of determining concentration of glucose in blood

  • US 6,841,389 B2
  • Filed: 02/05/2002
  • Issued: 01/11/2005
  • Est. Priority Date: 02/05/2001
  • Status: Expired due to Fees
First Claim
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1. A method of determining glucose concentration G(t) in blood comprising:

  • a) at a preliminary measurement stage, measuring the values of impedance or a component of impedance between the electrodes placed on the skin of a patient and invasively measuring the values of a glucose concentration Ginv(t) of the patient;

    b) determining parameters a0, q and a1 in an expression G

    (t)
    =G1

    e-a0

    t
    +q+a1

    e-a0

    t




    0t


    N

    (x)


    ea0

    x




    x
    ;



    by using the measured values of impedance or the component of impedance and the measured values of the glucose concentration Ginv(t) and approximating Ginv(t) to G(t); and

    c) independently of when and where steps a) and b) were performed, non-invasively measuring impedance or a component of impedance between electrodes placed on the skin of the patient and calculating the glucose concentration G(t) according to the expression, wherein step c) can be repeated without repeating steps a) and b).

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