Hemodialysis system

• US 6,843,779 B1
• Filed: 09/17/2001
• Issued: 01/18/2005
• Est. Priority Date: 09/17/2001
• Status: Expired due to Fees

• Current Assignee: Mirimedical LLC
• Original Assignee: Mirimedical LLC
• Inventors: Andrysiak, Philip, Mishkin, Gary
• Primary Examiner(s): Bianco, Patricia
• Application Number:
  US09/953,301
• Time in Patent Office: 1,219 Days
• Field of Search: 604/4.01, 604 501- 504, 604/65, 604/67, 422/44, 422/99, 422/101, 422/103, 210645- 47, 210650- 51, 210/739, 210/741, 210/767, 210/790, 210/85, 210 87- 89, 210/97, 210/102, 210/143, 210/194, 2101951-1952, 210/252, 210/255, 2102571-2572, 210/259, 210/260, 210/321.6, 21032171-32172, 210/321.75, 210/321.84
• US Class Current: 604/5.01
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3403 Regulation parameters
• CPC Class Codes: A61M 1/3417 using distinct filters for dialysis and ultra-filtration
• CPC Class Codes: A61M 1/36 Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 39/286 Wedge clamps, e.g. roller clamps with inclined guides
• CPC Class Codes: B01D 61/32 Controlling or regulating

Abstract

An apparatus and method for use in blood dialysis. The apparatus includes: two dialyzers each containing a semipermeable membrane that divides the dialyzer into a blood compartment and a dialysate compartment; a blood compartment connecting line connecting the blood compartments of the dialyzers together in series; blood connecting lines for connecting the blood compartments to the vascular system of a patient; a dialysate compartment connecting unit connecting the dialysate compartments of the dialyzers together in series; and dialysate connecting lines for connecting the dialysate compartments to a dialysis machine. The dialysate compartment connecting unit includes an adjustable flow varying device for controllably setting the rate of the flow of dialysate through the connecting unit.

Claims

1. An apparatus for use in blood dialysis comprising:

first and second dialyzers each containing a semipermeable membrane that divides the dialyzer into a blood compartment and a dialysate compartment, the dialysate compartment of each dialyzer being connectable to a dialysis machine;

a blood compartment connecting line connecting the blood compartments of said dialyzers together in series;

blood connecting lines for connecting said blood compartments to the vascular system of a patient; and

a dialysate compartment connecting unit connecting the dialysate compartments of said dialyzers together in series, wherein

said dialysate compartment connecting unit comprises an adjustable flow varying device for controllably setting the rate of the flow of dialysate through said connecting unit, said device being constructed to progressively vary the dialysate flow rate through said connecting unit,

said dialysate compartment connecting unit comprises a flexible tube and said adjustable flow varying device comprises a roller clamp composed of a roller that is movable along a path to progressively constrict said tube, and

said dialysate compartment connecting unit further comprises a hollow rod installed within, and having a smaller diameter than, said flexible tube, said roller clamp being operative to not deform said hollow rod so that said hollow rod defines a minimum dialysate flow path when said flexible tube is fully constricted.

2. The apparatus of claim 1 wherein said hollow rod is substantially rigid.

3. The apparatus of claim 1 wherein:

said roller has two lateral cylindrical parts for engaging said flexible tube, said lateral cylindrical parts being spaced from one another along the axis of said roller; and

said hollow rod is disposed in a region between said lateral cylindrical parts.

5. A method for performing dialysis on a patient with the apparatus according to claim 1, comprising:

connecting the dialysate compartments to a dialysis machine;

connecting the blood connecting lines to the vascular system of a patient;

placing the dialysis machine into operation; and

setting the rate of flow of the dialysate by adjusting the flow varying device to establish a selected relative pressure in the dialyzers.

6. The method of claim 5 wherein said step of setting comprises adjusting the flow varying device during a dialysis procedure.

4. An apparatus for use in blood dialysis comprising:

first and second dialyzers each containing a semipermeable membrane that divides the dialyzer into a blood compartment and a dialysate compartment, the dialysate compartment of each dialyzer being connectable to a dialysis machine;

a blood compartment connecting line connecting the blood compartments of said dialyzers together in series;

blood connecting lines for connecting said blood compartments to the vascular system of a patient; and

a dialysate compartment connecting unit connecting the dialysate compartments of said dialyzers together in series, wherein

said dialysate compartment connecting unit comprises an adjustable flow varying device for controllably setting the rate of the flow of dialysate through said connecting unit, said device being constructed to progressively vary the dialysate flow rate through said connecting unit,

said dialysate compartment connecting unit comprises a flexible tube and said adjustable flow varying device comprises a roller clamp composed of a roller that is movable along a path to progressively constrict said tube, and

said dialysate compartment connecting unit further comprises a second tube connected in parallel with said flexible tube and disposed to not be deformed by said roller clamp to define a minimum dialysate flow path when said flexible tube is fully constricted.