Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors
First Claim
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1. A compound represented by the following structural formula:
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the enantiomer of the compound, a salt of the compound, or a salt of the enantiomer, wherein;
R4 is H2 or O; and
R6 is represented by the following structural formula;
wherein phenyl ring A is substituted or unsubstituted;
or when R4 is H2, R6 can further be —
H.
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Abstract
Disclosed is a novel enantiomeric synthesis cermamide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.
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Citations
2 Claims
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1. A compound represented by the following structural formula:
-
the enantiomer of the compound, a salt of the compound, or a salt of the enantiomer, wherein;
R4 is H2 or O; and
R6 is represented by the following structural formula;
wherein phenyl ring A is substituted or unsubstituted;
orwhen R4 is H2, R6 can further be —
H. - View Dependent Claims (2)
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Specification