Decentralized patient management method

• US 6,856,913 B1
• Filed: 05/14/1999
• Issued: 02/15/2005
• Est. Priority Date: 05/15/1998
• Status: Expired due to Fees

• Current Assignee: SSPT Proprietary Limited
• Original Assignee: Swineburn Limited
• Inventors: Silberstein, Richard B.
• Primary Examiner(s): Marschel, Ardin H.
• Application Number:
  US09/700,296
• Time in Patent Office: 2,104 Days
• Field of Search: 514/2, 514/44, 702/19, 703/11
• US Class Current: 702/19
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/161 Flicker fusion testing eye testing A61B3/00
• CPC Class Codes: A61B 5/378 Visual stimuli
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/70 relating to mental therapies, e.g. psychological therapy or autogenous training
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system (2) for evaluating the efficiency of therapeutic treatments of patients (40) located at remote sites (6) by communicating a cognitive task to the remote site via a network (10) which provides two-way communication between a central analysis site and the remote sites, presenting the task to the patient before, during, or after carrying out a therapeutic intervention or treatment, detecting brain response from the patient, and communicating this response to the central analysis site via the network.

Claims

1. A method of evaluating the efficacy of treatment of a neuropsychiatric disorder of a patient at a remote site comprising the steps of:

presenting a first cognitive task to the patient at the remote site;

recording a first steady state visually evoked potential (SSVEP) corresponding to when the patient is presented with the first cognitive task;

administering a dose of psychotropic medication to the patient;

presenting a second cognitive task to the patient at the remote site, the second cognitive task being similar to or the same as the first cognitive task;

recording a second steady state visually evoked potential (SSVEP) corresponding to when the patient is presented with the second cognitive task; and

assessing at a central site the efficacy of the psychotropic medication on the basis of differences between the first and second SSVEPs.

2. A method as claimed in claim 1 wherein the step of assessing the efficacy comprises the step of detecting changes in coherence of said first and second SSVEPs.

3. A method as claimed in claim 1 comprising the steps of obtaining first output signals representing the response of the patient'"'"'s brain to said first cognitive task;

obtaining second output signals representing the response of the patient'"'"'s brain to said second cognitive task whilst under the influence of said medication;

transmitting the first and second output signals to the central site; and

calculating the amplitude, phase and/or coherence of said first and second SSVEPs from said first and second signals respectively.

4. A method as claimed in claim 3 comprising the steps of transmitting from the central site to the remote site first and second input signals representative of said first and second cognitive tasks.

5. A method as claimed in claim 4 wherein the first and second input signals and the first and second output signals are transmitted via the Internet.

6. A method as claimed in claim 5 wherein there are a plurality of said remote sites.

7. A method as claimed in claim 5 wherein a report of the step of assessing the efficacy is transmitted to a clinician at the remote site.

8. A method as claimed in claim 1 wherein a clinician administers the dose of psychotropic medication to the patient at the remote site and a report on the step of assessing the efficacy of the psychotropic medication is transmitted to the clinician via the Internet.

9. A method as claimed in claim 8 wherein the dose is a test dose and said report comprises an indication whether or not the patient is likely to benefit from long term administration of the psychotropic medication.

10. A method as claimed in claim 8 wherein the first and second cognitive tasks are download from the Internet at the remote site.

11. A method as claimed in claim 1 wherein the psychotropic medication comprises a chemical compound or compounds used in the treatment of psychiatric, psychological, behavioural, educational or neurological disorders.

12. A method as claimed in claim 1 wherein the step of assessing the efficacy comprises the step of detecting changes in amplitude and/or phase of said first and second SSVEPs.

13. A method as claimed in claim 3 wherein the steps of obtaining first and second output signals are effected by placing electrodes on the scalp of the patient, the first and second output signals being produced on said electrodes and the step of assessing the efficacy comprises detecting changes in inter-electrode SSVEP coherence.