Implantable intravascular pressure determining device and method

• US 6,860,857 B2
• Filed: 02/19/2002
• Issued: 03/01/2005
• Est. Priority Date: 08/31/2001
• Status: Expired due to Fees

• Current Assignee: St. Jude Medical AB (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical AB (Abbott Laboratories Incorporated)
• Inventors: Hedberg, Seven-Erik, Nilsson, Kenth, Norén, Kjell
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US10/078,210
• Publication Number:
  US 20030045800A1
• Time in Patent Office: 1,106 Days
• Field of Search: 600485-503
• US Class Current: 600/486
• CPC Class Codes: A61B 5/02158 provided with two or more sensor elements
• CPC Class Codes: A61B 5/721 using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured

Abstract

In an implantable intravascular pressure determining device and method, a pressure sensor generates a raw pressure signal and an acceleration sensor measures acceleration in a patient. Time intervals are identified wherein the raw pressure signal accurately represents the intravascular pressure, these intervals being identified as the time intervals wherein the measured acceleration is below a predetermined threshold. The raw pressure signal is processed, to generate a processed signal which is used as an intravascular pressure signal, only in the aforementioned time intervals.

Claims

1. An implantable intravascular pressure determining device comprising:

a pressure sensor adapted for placement in a vascular system of a subject for generating a raw pressure signal;

an acceleration sensor, separate from said pressure sensor, adapted for measuring acceleration associated with said subject and for generating an acceleration signal corresponding to the measured acceleration, said acceleration signal being separate from said raw pressure signal;

an evaluation unit supplied with said raw pressure signal and said acceleration signal for identifying time intervals, in which said measured acceleration is below a predetermined threshold, and for generating, a control signal in said time intervals said evaluation unit identifying a maximum signal strength of said acceleration signal, and setting said predetermined threshold to a predetermined fraction of said maximum signal strength; and

a processor supplied with said raw pressure signal and said control signal for processing said raw pressure signal, to generate a processed signal corresponding to intravascular pressure, only in the time intervals represented by said control signal.

2. An implantable intravascular pressure determining device as claimed in claim 1 wherein said evaluation unit uses an amplitude of said acceleration signal, as a representative of said signal strength, for identifying said maximum signal strength.

3. An implantable intravascular pressure determining device as claimed in claim 1 wherein said evaluation unit samples an amplitude of said acceleration signal, to obtain a sampled momentary value of said acceleration signal, and wherein said evaluation unit uses said sampled momentary value, as a representative of said signal strength, for identifying said maximum signal strength.

4. An implantable intravascular pressure determining device as claimed in claim 1 wherein said evaluation unit repeatedly samples an amplitude of said acceleration signal to obtain a plurality of sampled momentary values, over a plurality of diastolic heart cycles intervals, and wherein said evaluation unit forms an average value of said plurality of sampled momentary values and compares said average value, as a representative of said signal strength, to said predetermined threshold to identify said time intervals.

5. An implantable intravascular pressure determining device as claimed in claim 4 wherein said evaluation unit forms said average value over a plurality of said diastolic heart cycle intervals in a range between 30 and 40.

6. An implantable intravascular pressure determining device as claimed in claim 4 wherein said processor processes said raw pressure signal to generate said processed signal corresponding to said intravascular pressure in at least one of said time intervals wherein said average value is substantially zero.

7. An implantable intravascular pressure determining device as claimed in claim 1 wherein said evaluation unit sets said predetermined threshold at a value which is less than 20% of said maximum signal strength.

8. An implantable intravascular pressure determining device as claimed in claim 1 further comprising an implantable heart stimulating device which is adapted to administer heart stimulating therapy to said subject, and wherein said implantable heart stimulating device generates said heart stimulating therapy dependent on said intravascular pressure indicated by said processed signal.

9. An implantable intravascular pressure determining device as claimed in claim 1 wherein said pressure sensor comprises a pressure transducer which generates a measured pressure signal and a filter supplied with said measured pressure signal for filtering said measured pressure signal to generate said raw pressure signal, and a cardiac electrode, adapted for insertion in a heart, in which said pressure transducer is disposed.

10. A method for determining intravascular pressure, comprising the steps of:

placing a pressure sensor in a vascular system of a subject and generating a raw pressure signal therewith;

placing an acceleration sensor, separate from said pressure sensor, in interacting relation with said subject and generating an acceleration signal representing acceleration experience by said subject, said acceleration signal being separate from said raw pressure signal;

identifying time intervals in which said raw signal accurately represents intravascular pressure, in which time intervals said acceleration signal is below a predetermined threshold;

identifying a maximum signal strength of said acceleration signal and setting said predetermined threshold as a predetermined fraction of said maximum signal strength; and

processing said raw pressure signal only in said time intervals to generate a processed signal corresponding to said intravascular pressure in said time intervals.

11. A method as claimed in claim 10 comprising using an amplitude of said acceleration signal as a representative of said signal strength for identifying said maximum signal strength.

12. A method as claimed in claim 10 comprising sampling an amplitude of said acceleration signal to obtain a sampled momentary value, and using said sampled momentary value as a representative of said signal strength for identifying said maximum signal strength.

13. A method as claimed in claim 10 comprising repeatedly sampling said acceleration signal to obtain a plurality of sampled momentary values, averaging said sampled momentary values to obtain a mean value, and using said mean value as a representative of said signal strength for identifying said maximum signal strength.

14. A method as claimed in claim 10 comprising setting said predetermined threshold to a value which is less than 20% of said maximum signal strength.

15. A method as claimed in claim 10 comprising adapting a heart stimulating therapy dependent on said intravascular pressure, and administering said heart stimulating therapy to said subject using an implantable heart stimulating device.

16. A method as claimed in claim 10 comprising generating said raw pressure signal with pressure sensor comprising a pressure transducer which generates a measured pressure signal, and a filter supplied with said measured pressure signal which filters measured pressure signal to generate said raw pressure signal, and inserting said pressure transducer in a heart as a part of a cardiac electrode.