Apparatus and method for chronically monitoring heart sounds for deriving estimated blood pressure
First Claim
1. A method for deriving an estimated blood pressure of a patient, comprising the steps of:
- sensing first heart sound signals;
generating blood pressure estimation parameters in response to the first heart sound signals;
sensing second heart sound signals and cardiac depolarizations corresponding to the second heart sound signals; and
determining an estimated blood pressure in response to the second heart sound signals, the cardiac depolarizations corresponding to the second heart sound signals, and the generated blood pressure estimation parameters.
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Abstract
A minimally invasive, implantable heart sound and ECG monitor and associated method for deriving blood pressure from heart sound data. The device is equipped with an acoustical sensor for detecting first and second heart sounds which are sampled and stored during sensing windows following R-wave and T-wave detections, respectively. ECG and heart sound data are stored in a continuous, looping memory, and segments of data are stored in long-term memory upon an automatic or manual data storage triggering event. Estimated blood pressure is calculated based on custom spectral analysis and processing of the first and second heart sounds. A calibration method includes measuring a patient'"'"'s blood pressure using a standard clinical method and performing regression analysis on multiple spectral variables to identify a set of best fit weighted equations for predicting blood pressure. Concurrent ECG and estimated blood pressure may be displayed for review by a physician.
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Citations
20 Claims
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1. A method for deriving an estimated blood pressure of a patient, comprising the steps of:
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sensing first heart sound signals;
generating blood pressure estimation parameters in response to the first heart sound signals;
sensing second heart sound signals and cardiac depolarizations corresponding to the second heart sound signals; and
determining an estimated blood pressure in response to the second heart sound signals, the cardiac depolarizations corresponding to the second heart sound signals, and the generated blood pressure estimation parameters. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An implantable medical device system for deriving an estimated blood pressure of a patient, comprising:
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a first sensing portion sensing cardiac depolarizations;
a second sensing portion sensing heart sounds and generating corresponding heart sound signals including first heart sound signals and second sound heart signals;
a storage device;
a control circuit receiving data from the first sensing portion and the second sensing portion and controlling storage of the sensed cardiac depolarizations and the heart sound signals in the storage device;
an external device receiving the sensed cardiac depolarizations and the heart sound signals from the storage device, generating blood pressure estimation parameters in response to the first heart sound signals, and determining an estimated blood pressure in response to the second heart sound signals, the cardiac depolarizations corresponding to the second heart sound signals, and the generated blood pressure estimation parameters. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. An implantable medical device system for deriving an estimated blood pressure of a patient, comprising:
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means for sensing first heart sound signals;
means for generating blood pressure estimation parameters in response to the first heart sound signals;
means for sensing second heart sound signals and cardiac depolarizations corresponding to the second heart sound signals; and
means for determining an estimated blood pressure in response to the second heart sound signals, the cardiac depolarizations corresponding to the second heart sound signals, and the generated blood pressure estimation parameters.
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Specification