Apparatus for producing blood component products

• US 6,869,411 B2
• Filed: 10/30/2003
• Issued: 03/22/2005
• Est. Priority Date: 07/10/1992
• Status: Expired due to Term

• Current Assignee: Terumo BCT, Inc. (Terumo Corporation)
• Original Assignee: Gambro, Inc. (DaVita Incorporated)
• Inventors: Langley, Robert Warner, Dumont, Larry Joe
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): Deak, Leslie R.
• Application Number:
  US10/699,358
• Publication Number:
  US 20040096814A1
• Time in Patent Office: 509 Days
• Field of Search: 604/4.01, 604/5.01, 604/6.01, 604/6.04, 436/177, 422/72, 422/73, 422/67, 128/DIG.13, 210/781, 210/782, 210/645
• US Class Current: 604/6.01
• CPC Class Codes: A61M 1/02 Blood transfusion apparatus blood infusion by syringes A61M5/14
• CPC Class Codes: A61M 1/30 Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/303 having a reservoir for treated blood to be returned
• CPC Class Codes: A61M 1/3696 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: A61M 1/385 taking into account of the patient characteristics
• CPC Class Codes: A61M 2202/0415 Plasma
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: Y10T 436/101666 Particle count or volume standard or control [e.g., platelet count standards, etc.]
• CPC Class Codes: Y10T 436/115831 Condition or time responsive
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/25375 Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Abstract

A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two on-line yield determination techniques are utilized to determine the yield for the harvested blood components. One is a predetermined yield prediction technique and the second is a predetermined yield monitoring technique, each of which are individually calibrated in relation to a predetermined off-line yield determination technique. The predetermined yield prediction and monitoring techniques each provide the yield for the harvested blood components and each is then utilized to provide a determined yield. Consequently, when the harvested blood components are packaged the determined yield my be associated therewith, thereby providing a blood component product.

Claims

1. A system for providing a blood component product, comprising:

a blood component collection device;

a blood component yield predictor associated with said blood component collection device; and

means for calibrating said blood component yield predictor to a blood component yield counter, said blood component yield counter providing blood component yield determination capabilities, wherein a predicted yield value, generated by said blood component yield predictor from a blood component collection procedure in which a blood component collection is provided by said blood component collection device, is adjusted to an adjusted predicted yield value, and wherein a blood component yield associated with said blood component collection to define a blood component product is based on said adjusted predicted yield value.

2. A system, as claimed in claim 1, wherein said blood component collection device comprises a centrifuge.

3. A system, as claimed in claim 1, wherein said blood component yield predictor comprises a processor, a primary yield prediction algorithm which generates said adjusted predicted yield value, and a plurality of ancillary yield prediction algorithms which provide information used by said primary yield prediction algorithm.