Circumferential ablation device assembly

• US 6,872,205 B2
• Filed: 04/25/2002
• Issued: 03/29/2005
• Est. Priority Date: 05/09/1997
• Status: Expired due to Term

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Ross, Michael Ronald, Lesh, Michael D., Langberg, Jonathan J., Peacock, James C. III
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US10/133,523
• Publication Number:
  US 20020115995A1
• Time in Patent Office: 1,069 Days
• Field of Search: 606/32, 606/37, 606/40, 606 41- 50, 606/195, 607101-102, 607/122, 607/98, 607/99, 604/113
• US Class Current: 606/41
• CPC Class Codes: A61B 18/00 Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body eye surgery A61F9/007; ear surgery A61F11/00
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22054 with two balloons
• CPC Class Codes: A61B 2017/22067 Blocking; Occlusion A61B2017/22054 takes precedence
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/00273 Anchoring means for temporary attachment of a device to tissue
• CPC Class Codes: A61B 2018/00285 Balloons
• CPC Class Codes: A61B 2018/00291 using suction
• CPC Class Codes: A61B 2018/00369 Heart valves
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00815 measured by a thermistor
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/00898 Alarms or notifications created in response to an abnormal condition
• CPC Class Codes: A61B 2018/00994 : combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described. The expandable member is also adapted to conform to the pulmonary vein in the region of its ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length which has a distally reducing outer diameter. A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive “maze”-type procedure in the region of the pulmonary vein ostia in the left ventricle.

Claims

1. An apparatus for treating atrial arrhythmia in a patient, comprising:

delivery member with a proximal end portion and a distal end portion that is adapted to be positioned at least in part at a location where a pulmonary vein extends from an atrium;

an ablation element that is located along the distal end portion of the delivery member, is constructed to couple to an ablation actuator, and is adapted to be positioned along a region of tissue at least in part at a the location;

an anchor that is located along the distal end portion of the delivery member and is constructed to be positioned within the pulmonary vein to engage a pulmonary vein wall at an anchoring position along the pulmonary vein such that the ablation element is substantially secured along the location;

wherein said anchor comprises an expandable member that is constructed to expand to a sufficient outer diameter to engage a wall of the pulmonary vein at the anchoring position;

a perfusion passageway that is constructed to allow a volume of blood to flow from a region distally of the expandable member, along the pulmonary vein across the expandable member, and proximally of the expandable member when the expandable member is xpanded and engaged to the wall of the pulmonary vein at the anchoring position;

wherein the perfusion passageway comprises a perfusion lumen extending between a distal port along the distal end portion and a proximal port located proximally of the distal port along the distal end portion, and wherein the expandable member is located along the distal end portion between the distal and proximal ports; and

wherein the ablation element is located at least in part proximally of the anchor with respect to the delivery member.

2. A tissue ablation device assembly, comprising:

a delivery member having a proximal end portion, a distal end portion, and a longitudinal axis;

a radially extendable member adapted to engage a pulmonary vein and disposed along the distal end portion of the delivery member;

an ablation element coupled to the distal end portion, the ablation element being adapted to be positioned at a location where a pulmonary vein extends from an atrium and being configured such that the assembly is only capable of ablatively coupling to a single arcuate area;

wherein the single arcuate area is adapted to correspond with a single arcuate region of cardiac tissue along a circumference circumscribing a longitudinal axis of the pulmonary vein at the location; and

wherein the assembly is adapted to inhibit blood from contacting the ablation element when the ablation element is ablatively coupled to the region of tissue.

3. A tissue ablation device assembly as recited in claim 2, wherein the ablation member is adapted to substantially prevent blood from contacting the region of tissue when the ablation element is ablatively coupled to the region of tissue.

4. A tissue ablation device assembly comprising:

an ablation member adapted to be positioned at a location where a pulmonary vein extends from an atrium and configured such that the assembly is only capable of simultaneously ablating a single circumferential region of tissue at the location;

wherein the ablation member comprises an ablation element which is adapted to contact the region of tissue.

5. A tissue ablation device assembly comprising:

an ablation member with an ablation element configured such that the assembly is only capable of ablatively coupling to a single circumferential area;

wherein the single circumferential area is adapted to correspond with a single circumferential region of tissue at a location where a pulmonary vein extends from an atrium;

wherein the ablation element is adapted to ablate the single circumferential region of tissue at the location without substantially repositioning the ablation element; and

wherein the ablation member is adapted to inhibit blood from contacting the ablation element when the ablation element is ablatively coupled to the region of tissue.

6. A tissue ablation device assembly as recited in claim 5, wherein the ablation member is adapted to substantially prevent blood from contacting the ablation element when the ablation element is ablatively coupled to the region of tissue.