Human protease inhibitor and polynucleotides encoding the same

• US 6,875,587 B2
• Filed: 04/17/2003
• Issued: 04/05/2005
• Est. Priority Date: 12/18/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Hu, Yi, Walke, D. Wade, Nepomnichy, Boris
• Primary Examiner(s): Prouty, Rebecca E.
• Assistant Examiner(s): Walicka, Malgorzata A.
• Application Number:
  US10/419,277
• Publication Number:
  US 20030224498A1
• Time in Patent Office: 719 Days
• Field of Search: 530/350, 536/23.5, 536/24.33, 435/69.2, 435/320.1, 435/252.33, 435/252.31, 435/254.21, 435/254.23, 435/325, 435/410, 435/69.1
• US Class Current: 435/69.2
• CPC Class Codes: A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• CPC Class Codes: C07K 14/47 from mammals
• CPC Class Codes: C07K 14/8107 Endopeptidase (E.C. 3.4.21-99) inhibitors
• CPC Class Codes: C07K 14/8121 Serpins

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications

Claims

1. A host cell comprising an expression vector comprising a nucleic acid sequence that encodes the amino acid sequence of SEQ ID NO:

2.

2. The host cell of claim 1 wherein said nucleic acid sequence is that of SEQ ID NO:

1.

3. A method of producing a protein, comprising culturing the cell of claim 1 under conditions permitting expression of the polypeptide.

4. A method of producing a protein, comprising culturing the cell of claim 2 under conditions permitting expression of the polypeptide.

5. An expression vector comprising the nucleic acid sequence of SEQ ID NO:

1.