Dual chamber dissolution container with passive agitation

• US 6,878,338 B2
• Filed: 05/06/2002
• Issued: 04/12/2005
• Est. Priority Date: 05/04/2001
• Status: Expired due to Fees

• Current Assignee: Prismedical Corporation
• Original Assignee: Prismedical Corporation
• Inventors: Fitzgerald, Carolyn, Taylor, Michael A.
• Primary Examiner(s): Ludlow, Jan M.
• Application Number:
  US10/141,501
• Publication Number:
  US 20030012690A1
• Time in Patent Office: 1,072 Days
• Field of Search: 422/61, 422/100, 422/102, 366/336, 366/340, 604/82, 604/85, 604/87, 604/92
• US Class Current: 422/430
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/286 upon internal pressure increase, e.g. pierced or burst A61M5/283 takes precedence
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: B01F 21/00 Dissolving separating by dissolving B01D; dissolving to effect cooling F25D5/00
• CPC Class Codes: B01F 33/5011 portable during use, e.g. hand-held
• CPC Class Codes: B01F 33/50112 of the syringe or cartridge type
• CPC Class Codes: B01F 35/713 comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges containers or packages per se B65D
• CPC Class Codes: B01J 19/1812 Tubular reactors
• CPC Class Codes: B01J 19/26 Nozzle-type reactors, i.e. the distribution of the initial reactants within the reactor is effected by their introduction or injection through nozzles
• CPC Class Codes: B01J 8/0278 Feeding reactive fluids for solid material B01J8/0015

Abstract

A reagent dissolution device and methods of using the same, wherein the device comprises a housing (40), a diluent (25), and at least one reagent bed (35), wherein the diluent (25) and the at least one reagent bed (35) are separated by a friable barrier (50) and a flow distribution disk (100). Alternate embodiments include chambers with a plurality of reagent beds as well as chambers for the mixing of two or more liquid reagents.

Claims

1. A reagent delivery device comprising:

a housing defining a fluid flow path therethrough,

at least one reagent bed within the housing;

a compression component exerting pressure upon the at least one reagent bed; and

a flow distribution disk positioned upstream of the at least one reagent bed, the disk including at least one angled flow passage therethrough, wherein the at least one angled flow passage is disposed at an angle that is disposed at a range of 30 to 75 degrees with respect to either a vertical axis or a horizontal axis of the disk.

2. The reagent dissolution device of claim 1, wherein the compression component is porous and expandable and positioned within the housing and upstream of the flow distribution disk.

3. The reagent dissolution device of claim 1, wherein the flow distribution disk comprises a top layer and an adjacently disposed bottom layer that form a distribution chamber.

4. The reagent dissolution device of claim 3, wherein the bottom layer is a porous plate.

5. The reagent dissolution device of claim 3, wherein the at least one angled flow passage is located in the bottom layer and comprises a plurality of directional channels bounded by an inlet port and an outlet port.

6. The reagent dissolution device of claim 1, further comprising a pressure-generating plunger.

7. The reagent dissolution device of claim 1, further comprising a pressure-generating spring.

8. The reagent dissolution device of claim 1, further comprising a diluent.

9. The reagent dissolution device of claim 8, wherein the diluent comprises a first liquid reagent.

10. The reagent dissolution device of claim 9, wherein the at least one reagent bed contains a second liquid reagent.

11. The reagent dissolution device of claim 1, wherein the at least one reagent bed comprises a dry reagent bed.

12. The reagent dissolution device of claim 1, wherein the flow distribution disk is slidably disposed within the housing between the compression component and the at least one reagent bed.

13. A reagent

delivery device comprising:

a housing defining a fluid path therethrough;

a dry reagent bed within the housing;

a compression component exerting pressure on the dry reagent bed; and

a flow distribution disk positioned upstream of the dry reagent bed, the disk including at least one angled flow passage therethrough, wherein the at least one angled flow passage comprises a plurality of directional channels disposed at a range from 45 to 75 degrees with respect to a vertical axis of the disk.

14. The reagent delivery device of claim 13, wherein the plurality of directional channels are disposed at a range from 55 to 65 degrees with respect to the vertical axis of the disk.

15. A reagent delivery device, comprising:

a housing defining a fluid flow path therethrough;

at least one reagent bed within the housing; and

a flow distribution disk positioned upstream of the at least one reagent bed, the disk including at least one flow passage therethrough, the flow passage being angled between 45 and 75 degrees with respect to a vertical axis of the disk.

16. The reagent delivery device of claim 15, further comprising a porous expansion component upstream of the flow distribution disk.

17. The reagent delivery device of claim 15, wherein the flow distribution disk is slidably disposed within the housing between the compression component and the at least one reagent bed.

18. The reagent delivery device of claim 15, further comprising a pressure-generating plunger.

19. The reagent delivery device of claim 15, further comprising a pressure-generating spring.

20. The reagent delivery device of claim 15, further comprising a diluent.

21. The reagent delivery device of claim 20, wherein the diluent comprises a first liquid reagent.

22. The reagent delivery device of claim 21, wherein the at least one reagent bed contains a second liquid reagent.

23. The reagent delivery device of claim 15, wherein the at least one reagent bed comprises a dry reagent bed.