Method and apparatus for detection and treatment of tachycardia and fibrillation

• US 6,879,856 B2
• Filed: 03/21/2001
• Issued: 04/12/2005
• Est. Priority Date: 03/21/2000
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Gillberg, Jeffrey M., Stadler, Robert W., Gunderson, Bruce D., Olson, Walter H.
• Primary Examiner(s): Evanisko, George R.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/814,251
• Publication Number:
  US 20010034539A1
• Time in Patent Office: 1,483 Days
• Field of Search: 600/509, 600/515, 600/516, 600/518, 600/519, 600/521, 607/4, 607/5, 607/7, 607/8, 607/9, 607/14, 607/15, 607/25
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

The invention relates to devices that detect and/or treat tachyarrhythmias. The invention includes software systems that distinguish among various tachyarrhythmias in order to provide treatment for specific tachyarrhythmias. One aspect of the invention employs a methodology to provisionally detect ventricular tachycardia and/or fibrillation and thereafter apply a discrimination function to a series of measured intervals preceding the provisional detection. Discrimination is accomplished by sorting the intervals preceding provisional detection into bins corresponding to interval ranges and examining the relative distribution of the intervals within the bins.

Claims

1. Apparatus for treating tachyarrhythmias, comprising:

means for delivering a first therapy to a patient'"'"'s heart to treat tachycardia and a second therapy to said patient'"'"'s heart to treat fibrillation;

means for sensing an electrical signal from said patient'"'"'s heart indicative of a depolarization of a chamber or chambers of said patient'"'"'s heart;

means for measuring a time interval between depolarizations;

means for storing the measured depolarization intervals;

means for detecting an occurrence of a tachyarrhythmia based upon the measured depolarization intervals; and

means responsive to the detection of an occurrence of a tachyarrhythmia for discriminating between tachycardia and fibrillation and for selecting between said first and second therapies;

said discrimination and therapy selection means including;

(i) means for sorting a predetermined number of the measured depolarization intervals into a plurality of interval range bins;

(ii) means for determining the number of measured depolarization intervals within each of the interval range bins;

(iii) means for defining a discrimination criterion based on determining whether designated ones of the plurality of interval range bins have at least a predetermined threshold number of measured depolarization intervals within them, wherein the threshold number is set as a value which decreases as a function of the length of the intervals between depolarizations; and

(iv) means for triggering delivery of the first therapy if the discrimination criterion is met and for triggering delivery of the second therapy if the discrimination criterion is not met.

2. The apparatus of claim 1, wherein the discrimination criterion is used to distinguish between fast VT and VF, and if the discrimination criterion is met, the tachyarrhythmia is determined to be a fast ventricular tachycardia, the first therapy is delivered;

and if the discrimination criterion is not met, the tachyarrhythmia is determined to be fibrillation and the second therapy is delivered.

3. The apparatus of claim 1, wherein the discrimination criterion is used to distinguish between VT and fast ventricular rhythms due to atrial fibrillation (VT vs. AF), and if the discrimination criterion is met, the tachyarrhythmia is determined to be a ventricular tachycardia and a tachycardia therapy is delivered;

and if the discrimination criterion is not met, the tachyarrhythmia is determined to be due to atrial fibrillation and no therapy is delivered.

4. The apparatus of claim 1, wherein the predetermined threshold number of intervals required in order to meet the discrimination criterion is variable as a function of the underlying rate of the detected tachyarrhythmia.

5. The apparatus of claim 4, wherein the threshold number varies as a decreasing function of the tachyarrhythmia cycle lengths of a preceding series of depolarizations;

and wherein the 75th percentile cycle length of the preceding sequence of depolarizations is employed as a measurement metric, with the threshold number of intervals expressed as a percentage of intervals binned decreasing from 100% to 30% in a linear fashion as the 75th percentile cycle length increases.

6. The apparatus of claim 5, wherein the 75th percentile cycle length of the preceding series of depolarizations is calculated by selecting the fourth longest interval out of the preceding twelve measured depolarization intervals.

7. Apparatus for treating tachyarrhythmias, comprising:

means for delivering a first therapy to a patient'"'"'s heart to treat tachycardia and a second therapy to said patient'"'"'s heart to treat fibrillation;

means for sensing an electrical signal from said patient'"'"'s heart indicative of a depolarization of a chamber or chambers of said patient'"'"'s heart;

means for measuring a time interval between depolarizations;

means for storing the measured depolarization intervals;

means for detecting an occurrence of a tachyarrhythmia based upon the measured depolarization intervals; and

means responsive to the detection of an occurrence of a tachyarrhythmia for discriminating between tachycardia and fibrillation and for selecting between said first and second therapies;

said discrimination and therapy selection means including;

(i) means for sorting a predetermined number of the measured depolarization intervals into a plurality of interval range bins;

(ii) means for determining the number of measured depolarization intervals within each of the interval range bins;

(iii) means for defining a discrimination criterion based on determining whether designated ones of the plurality of interval range bins have at least a predetermined threshold number of measured depolarization intervals within them, wherein the threshold number is set as a value which increases as an inverse function of a defined percentile of the length of intervals over a sequence of a predetermined number of intervals between depolarization; and

(iv) means for triggering delivery of the first therapy if the discrimination criterion is met and for triggering delivery of the second therapy if the discrimination criterion is not met.

8. Apparatus for treating tachyarrhythmias, comprising:

means for delivering a first therapy to a patient'"'"'s heart to treat tachycardia and a second therapy to said patient'"'"'s heart to treat fibrillation;

means for sensing an electrical signal from said patient'"'"'s heart indicative of a depolarization of a chamber or chambers of said patient'"'"'s heart;

means for measuring a time interval between depolarizations;

means for storing the measured depolarization intervals;

means for detecting an occurrence of a tachyarrhythmia based upon the measured depolarization intervals; and

means responsive to the detection of an occurrence of a tachyarrhythmia for discriminating between tachycardia and fibrillation and for selecting between said first and second therapies;

said discrimination and therapy selection means including;

(i) means for sorting a predetermined number of the measured depolarization intervals into a plurality of interval range bins;

(ii) means for determining the number of measured depolarization intervals within each of the interval range bins;

(iii) means for defining a discrimination criterion based on determining whether designated ones of the plurality of interval range bins have at least a predetermined threshold number of measured depolarization intervals within them, wherein the threshold number is set as a value which increases as an inverse function of the 75th percentile of the length of intervals over a sequence of a predetermined number of intervals between depolarizations; and

(iv) means for triggering delivery of the first therapy if the discrimination criterion is met and for triggering delivery of the second therapy if the discrimination criterion is not met.