Method and apparatus for rapid screening of volatiles

• US 6,881,585 B1
• Filed: 03/06/2000
• Issued: 04/19/2005
• Est. Priority Date: 03/06/2000
• Status: Expired due to Fees

• Current Assignee: Sabic Innovative Plastics IP BV (Government of Saudi Arabia)
• Original Assignee: General Electric Company
• Inventors: Lemmon, John Patrick, May, Ralph Joseph, Potyrailo, Radislav Alexandrovich, Carnahan, James Claude
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Cole, Monique T.
• Application Number:
  US09/519,330
• Time in Patent Office: 1,870 Days
• Field of Search: 436/151, 73/10.2, 73/190.1, 73/191, 73/240.4, 733/350.1, 73/617.7, 738/632.1
• US Class Current: 436/151
• CPC Class Codes: G01N 33/0009 General constructional details of gas analysers, e.g. portable test equipment devices for withdrawing samples in the gaseous state G01N1/22
• CPC Class Codes: G01N 33/0047 Organic compounds

Abstract

In one embodiment, the present method includes the steps of introducing a volume of a sample into a vapor delivery line and volatilizing at least a portion of the volume as it is carried through the vapor delivery line. At least a portion of the volatilized volume contacts a sensor element, which produces a signal that is monitored to reveal information about the sample. All components upstream of the sensor element are substantially free of sorbent materials so that the sample volume does not contact a substantially sorbent material before contacting the sensor element.

Claims

1. A method for rapidly screening volatile substances in a sample, said method comprising the steps of:

a) introducing a volume of said sample into a vapor delivery line;

b) volatilizing at least a portion of said volume as said volume is carried through said vapor delivery line;

c) contacting at least a portion of said volatilized with a sensor element, wherein the sensor element is coated with a hard-soft block elastomer; and

, wherein said volume does not contact a substantially sorbent material before contacting said sensor element; and

d) monitoring a signal from said sensor element,

wherein said signal comprises a response of said sensor element to a temporally-determined variation in a concentration of said vapor proximate said sensor element, and wherein said signal is capable of providing both qualitative and quantitative information about said volatile substances in said sample.

2. The method of claim 1, wherein said sensor element is an optical sensor element.

3. The method of claim 1, wherein said sensor element is an electrochemical sensor element.

4. The method of claim 1, wherein said sensor element comprises a semiconductor.

5. The method of claim 1, wherein said sensor element comprises a quartz crystal.

6. The method of claim 1, wherein the hard-soft block elastomer comprises a silicone polyimide.

7. The method of claim 1, wherein said hard-soft block elastomer comprises a block dimethylsiloxane-carbonate copolymer.

8. The method of claim 1, wherein step c) comprises contacting at least a portion of said volatilized volume with an array of sensor elements.

9. The method of claim 1, wherein said volume is carried through said vapor delivery line by an inert carrier gas.

10. The method of claim 9, wherein said inert carrier gas is flowing through said vapor delivery line at a rate of between about 1 mL/min and about 1000 mL/min.

11. The method of claim 10, wherein said inert carrier gas is flowing through said vapor delivery line at a rate of between about 150 mL/min and about 500 mL/min.

12. The method of claim 1, wherein said signal from said sensor element is monitored as a function of time.

13. The method of claim 12, wherein said signal is monitored with at least one frequency counter to produce data.

14. The method of claim 13, wherein said data are stored in a computer.

15. The method of claim 9, further comprising the step of controlling the flow of said inert carrier gas through said vapor delivery line with flow controllers in communication with a computer.

16. A method for rapidly screening volatile substances in a simple, said method comprising the steps of:

a) introducing a volume of said sample into a vapor delivery line;

b) volatilizing at least a portion of said volume as said volume is carried through said vapor delivery line;

c) contacting at least a portion of said volatilized volume with a sensor element comprising a quartz crystal and a chemically sensitive film proximate the surface of said crystal, wherein the chemically sensitive film comprises a hard-soft block elastomer; and

wherein said volume does not contact a substantially sorbent material before contacting said sensor element; and

d) monitoring a measured property of said chemically sensitive film as a function of time to yield both qualitative and quantitative information about said volatile substances in said sample.

17. A method for rapidly screening volatile substances in a sample, the method comprising the steps of:

(a) introducing a volume of said sample into a vapor delivery line;

(b) volatilizing at least a portion of said volume as said volume is carried through said vapor delivery line;

(c) contacting at least a portion of said volatilized volume with a sensor element, wherein the sensor element is coated with a hard-soft block elastomer; and

wherein said volume does not contact a substantially sorbent material before contacting said sensor element; and

(d) monitoring a signal from said sensor element as a function of time to yield both qualitative and quantitative information about said volatile substances in said sample.

18. The method of claim 17, wherein said volume is carried through said vapor delivery line by an analyte-free carrier gas.

19. The method of claim 18, further comprising the step of controlling the flow of said analyte-free carrier through said vapor delivery line with flow controllers in communication with a computer.

20. The method of claim 17, further comprising purging the system to remove any remaining analyte vapors prior to introduction of a second sample into said vapor delivery line.

21. The method of claim 17, wherein the sensor element is coated with a chemically sensitive material to form a chemically sensitive film proximate the surface of the sensor element.

22. The method of claim 17, wherein said sensor comprises a quartz crystal.

23. The method of claim 17, wherein step (c) comprises contacting at least a portion of said volatilized volume with an array of sensor elements.

24. The method of claim 17, wherein said sensor element is an optical element.

25. The method of claim 17, wherein said sensor element is an electrochemical element.