Sutures and coatings made from therapeutic absorbable glass
First Claim
Patent Images
1. A coating composition for a surgical device comprising:
- therapeutic water-soluble glass and a biocompatible polymer selected from the group consisting of bioabsorbable polymers and non-bioabsorbable polymers, wherein the coating composition is adapted to coat the surgical device.
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Abstract
Sutures fabricated from and/or coated with compositions including water-soluble glass are described herein. Pledgets containing water-soluble glass within the interstices of the pledget and/or coated with compositions including water-soluble glass are also described herein. The water-soluble glass optionally includes a therapeutic agent, e.g., silver to promote wound repair.
221 Citations
75 Claims
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1. A coating composition for a surgical device comprising:
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therapeutic water-soluble glass and a biocompatible polymer selected from the group consisting of bioabsorbable polymers and non-bioabsorbable polymers, wherein the coating composition is adapted to coat the surgical device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 74, 75)
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- 17. A suture coated with a coating composition, the coating composition comprising therapeutic water-soluble glass and a biocompatible polymer selected from the group consisting of bioabsorbable polymers and non-bioabsorbable polymers.
- 26. A monofilament suture comprising therapeutic water-soluble glass and a polymer selected from the group consisting of biocompatible bioabsorbable polymer and biocompatible non-bioabsorbable polymer.
- 31. A multifilament suture comprising filaments fabricated from biocompatible therapeutic water-soluble glass.
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36. A method for preparing a suture having therapeutic activity comprising:
applying to the suture a coating composition including therapeutic water-soluble glass containing a therapeutically effective amount of a therapeutic agent. - View Dependent Claims (37, 38, 39, 40, 41, 42, 50)
- 43. A method of preparing a coating composition for a surgical device comprising dispersing therapeutic water-soluble glass and a polymer selected from the group consisting of biocompatible bioabsorbable polymer or biocompatible non-bioabsorbable polymer in a suitable solvent, wherein the coating composition is adapted to coat the surgical device.
- 51. A pledget comprising therapeutic water-soluble glass.
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66. A method for preparing a pledget having therapeutic activity comprising:
- providing therapeutic water-soluble glass;
providing a pledget; and
incorporating the therapeutic water-soluble glass into the pledget. - View Dependent Claims (67, 68, 69, 70, 71, 72, 73)
- providing therapeutic water-soluble glass;
Specification