Patient specific dosing contrast delivery systems and methods

• US 6,889,074 B2
• Filed: 12/29/2000
• Issued: 05/03/2005
• Est. Priority Date: 09/21/1994
• Status: Expired due to Fees

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Welch, Thomas R., Uber, Arthur E. III, Hirschman, Alan D., Almon-Martin, Rosemary
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US09/749,894
• Publication Number:
  US 20010056233A1
• Time in Patent Office: 1,586 Days
• Field of Search: 600/431, 600432-435, 604/30, 604/31, 604/33, 604/27, 604/28, 604/246, 604/65, 604/67, 604/36
• US Class Current: 600/431
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/80 voice-operated command
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: Y10S 128/12 Pressure infusion
• CPC Class Codes: Y10S 128/13 Infusion monitoring

Abstract

This invention relates generally to the field of medical devices for delivering contrast media during medical diagnostic and therapeutic imaging procedures and more particularly, this invention relates to improved contrast media delivery systems and methods of use which allow adjustment of contrast media concentration and injection parameters either before or during an injection procedure to provide patient specific dosing of contrast media, thus decreasing the waste and cost of these procedures while increasing their efficiency.

Claims

1. An injection system for injecting fluid into a patient, the injection system comprising:

a fluid delivery apparatus;

a fluid path structured to be disposed between the fluid delivery apparatus and the patient;

a control unit in communication with and operable to control the fluid delivery apparatus; and

a control mechanism in communication with the control unit, the control mechanism comprising a tactile feedback unit and a sensor that generates and sends a signal to the control unit,

whereby the control unit controls the injection of fluid into the patient in proportion to the signal.

2. The injection system of claim 1 wherein the sensor comprises a force sensor.

3. The injection system of claim 1 wherein the control mechanism is in fluid communication with the fluid path.

4. The injection system of claim 3 wherein the pressure generated by the fluid in the fluid path is communicated to the control mechanism.

5. The injection system of claim 1 wherein the tactile feedback unit comprises an actuator mechanism in communication with the sensor.

6. The injection system of claim 5 wherein the sensor senses movement of the actuator mechanism by an operator.

7. The injection system of claim 6 wherein the signal generated by the sensor is proportional to the movement of the actuator mechanism.

8. The injection system of claim 6 wherein the volume of injected fluid is proportional to the displacement of the actuator mechanism.

9. The injection system of claim 6 wherein the flow rate of injected fluid is proportional to the rate of displacement of the actuator mechanism.

10. The injection system of claim 6 wherein the flow rate of injected fluid is proportional to the displacement of the actuator mechanism.

11. The injection system of claim 5 wherein the actuator mechanism comprises a plunger.

12. The injection system of claim 5 wherein the flow rate of the fluid is controlled by the control unit.

13. The injection system of claim 1 wherein the sensor comprises a potentiometer.

14. The injection system of claim 1 wherein the control mechanism is reusable.

15. The injection system of claim 1 wherein the proportional relationship between the signal and the injection of fluid is a substantially linear relationship.

16. The injection system of claim 1, wherein the sensor is an integrated element of the control mechanism.

17. The injection system of claim 1, wherein the tactile feedback unit comprises a syringe and the sensor is disposed on a cradle coupled to the syringe.

18. The injection system of claim 1 wherein the sensor is configured to sense the pressure within the control mechanism.

19. The injection system of claim 1 wherein the sensor is configured to sense the pressure within the fluid path.

20. An injection system for injecting fluid into a patient, the injection system comprising:

a fluid delivery apparatus;

a fluid path structured to be disposed between the fluid delivery apparatus and the patient;

a manifold disposed in the fluid path between the fluid delivery apparatus and the patient;

a control unit in communication with and operable to control the fluid delivery apparatus; and

a control mechanism in communication with the control unit, the control mechanism comprising a tactile feedback unit and a sensor that generates and sends a signal to the control unit,

whereby the control unit controls the injection of fluid into the patient in proportion to the signal.

21. The injection system of claim 20 wherein the sensor comprises a force sensor.

22. The injection system of claim 20 wherein the control mechanism is in fluid communication with the fluid path.

23. The injection system of claim 22 wherein the pressure generated by the fluid in the fluid path is communicated to the control mechanism.

24. The injection system of claim 20 wherein the tactile feedback unit comprises an actuator mechanism in communication with the sensor.

25. The injection system of claim 24 wherein the sensor senses movement of the actuator mechanism by an operator.

26. The injection system of claim 25 wherein the signal generated by the sensor is proportional to the movement of the actuator mechanism.

27. The injection system of claim 25 wherein the volume of injected fluid is proportional to the displacement of the actuator mechanism.

28. The injection system of claim 25 wherein the flow rate of injected fluid is proportional to the rate of displacement of the actuator mechanism.

29. The injection system of claim 25 wherein the flow rate of injected fluid is proportional to the displacement of the actuator mechanism.

30. The injection system of claim 24 wherein the actuator mechanism comprises a plunger.

31. The injection system of claim 24 wherein the flow rate of the fluid is controlled by the control unit.

32. The injection system of claim 20 wherein the sensor comprises a potentiometer.

33. The injection system of claim 20 wherein the control mechanism is reusable.

34. The injection system of claim 20 wherein the proportional relationship between the signal and the injection of fluid is a substantially linear relationship.

35. The injection system of claim 20 wherein the control unit is in communication with and is operable to control the manifold.

36. The injection system of claim 20 wherein the manifold is manually operated.

37. The injection system of claim 20 wherein the manifold is power activated.

38. The injection system of claim 20 wherein the sensor is an integrated element of the control mechanism.

39. The injection system of claim 20 wherein the tactile feedback unit comprises a syringe and the sensor is disposed on a cradle coupled to the syringe.

40. An injection system for injecting fluid into a patient, the injection system comprising:

a fluid delivery apparatus;

a fluid path structured to be disposed between the fluid delivery apparatus and the patient;

a control unit in communication with and operable to control the fluid delivery apparatus; and

a control mechanism in communication with the control unit, the control mechanism comprising a sensor that generates and sends a signal to the control unit,

whereby the control unit is programmed to control the injection of fluid into the patient in proportion to the signal, wherein

the control mechanism further comprises a syringe, the sensor being formed on a cradle coupled to the syringe, and an actuator mechanism in communication with the sensor,

the sensor senses movement of the actuator mechanism by an operator, and

the signal generated by the sensor is proportional to the movement of the actuator mechanism.

41. The injection system of claim 40 wherein the control mechanism is hand-operated.

42. The injection system of claim 40 wherein the control mechanism is in fluid communication with the fluid path.

43. The injection system of claim 40 wherein the actuator mechanism comprises a plunger.

44. The injection system of claim 40 wherein the sensor comprises a potentiometer.

45. The injection system of claim 40 wherein the flow rate of the fluid is controlled by the control unit.

46. The injection system of claim 40 wherein the control mechanism is reusable.

47. The injection system of claim 40 wherein the volume of injected fluid is proportional to the displacement of the actuator mechanism.

48. The injection system of claim 40 wherein the flow rate of injected fluid is proportional to the rate of displacement of the actuator mechanism.

49. The injection system of claim 40 wherein the flow rate of injected fluid is proportional to the displacement of the actuator mechanism.

50. The injection system of claim 40 wherein the proportional relationship between the signal and the injection of fluid is a substantially linear relationship.

51. The injection system of claim 40 wherein the pressure generated by the fluid in the fluid path is communicated to the control mechanism.

52. The injection system of claim 40, further comprising a manifold disposed in the fluid path between the fluid delivery apparatus and the patient.

53. The injection system of claim 52 wherein the control unit is in communication with and is operable to control the manifold.

54. The injection system of claim 52 wherein the manifold is manually operated.

55. The injection system of claim 52 wherein the control mechanism is in fluid communication with the fluid pat.

56. The injection system of claim 52 wherein the manifold is power activated.

57. The injection system of claim 40 wherein the sensor is an integrated element of the control mechanism.

58. The injection system of claim 40 wherein the sensor is configured to sense the pressure within the control mechanism.

59. The injection system of claim 40 wherein the sensor is configured to sense the pressure within the fluid path.