Two-piece stent combination for percutaneous arterialization of the coronary sinus and retrograde perfusion of the myocardium

• US 6,893,413 B2
• Filed: 01/07/2002
• Issued: 05/17/2005
• Est. Priority Date: 01/07/2002
• Status: Expired due to Fees

• Current Assignee: Eric C. Martin
• Original Assignee: Eric C. Martin
• Inventors: Martin, Eric C.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): DEAK, LESLIE R
• Application Number:
  US10/036,441
• Publication Number:
  US 20030130611A1
• Time in Patent Office: 1,226 Days
• Field of Search: 604 8- 10, 604/6.16, 604/157, 604/264, 604/247, 623 11- 115, 623/1.23, 623/1.24, 623/1.3, 600/16
• US Class Current: 604/8
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2493 Transmyocardial revascularisation [TMR] devices
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0037 differing in height or in length
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

The present invention contemplates a method for percutaneously providing oxygenated blood retrogradely from the left ventricle via coronary sinus to the heart tissue without a significant left-to-right shunt. The present invention contemplates a two-piece stent combination generally having an arterializing stent and a restricting covered stent.

Claims

1. A two-piece stent combination for facilitating retrograde supply of oxygenated blood to heart tissue through a coronary sinus comprising:

an arterializing stent having a leading end configured to be positioned in a left ventricle and a trailing end configured to be positioned in a coronary sinus, and

a restricting covered stent having an underlying restricting stent and a covering, and having a coronary sinus distal end configured to be positioned in the coronary sinus, and a right atrial proximal end, and exhibiting a constriction between said coronary sinus distal end and said right atrial proximal end.

2. Two-piece stent combination according to claim 1, wherein a cross section of said restricting covered stent tapers toward said constriction.

3. The two piece stent combination according to claim 1, wherein a cross section of said restricting covered stent is appropriately sized to control blood flow from said coronary sinus into right atrium.

4. The two-piece stent combination according to claim 1, wherein said arterializing stent further exhibits a constriction along its length and a cross sectional tapering toward the constriction.

5. The two-piece stent combination according to claim 1, wherein a cross section of said arterializing stent is appropriately sized to control blood flow from said left ventricle into said coronary sinus.

6. The two-piece stent combination according to claim 1, wherein a cross section of said restricting covered stent at said constriction and a cross section of said arterializing stent are appropriately sized to keep pressure inside the coronary sinus from rising above about 50 mm Hg while avoiding excessive left-to-right shunting.

7. The two-piece stent combination according to claim 1, wherein a cross section of said restricting covered stent at said constriction and a cross section of said arterializing stent are appropriately sized to keep pressure inside said coronary sinus from rising above about half systemic pressure.

8. The two-piece stent combination according to claim 1, wherein said restricting covered stent and said arterializing stent allow compression to fit within a delivery catheter.

9. The two-piece stent combination according to claim 1, wherein said restricting covered stent and said arterializing stent allow expansion after delivery.

10. The two-piece stent combination according to claim 1, wherein said arterializing stent and said restricting covered stent are flexible.

11. The two-piece stent combination according to claim 1, wherein said covering of said restricting covered stent is inside underlying restricting stent.

12. The two-piece stent combination according to claim 1, wherein said covering of said restricting covered stent is outside said underlying restricting stent.

13. The two-piece stent combination according to claim 1, wherein said covering of said restricting covered stent partially covers said underlying restricting stent.

14. The two-piece stent combination according to claim 1, wherein said arterializing stent further comprises a covering.

15. The two-piece stent combination according to claim 14, wherein said covering of said arterializing stent is inside arterializing stent.

16. The two-piece stent combination according to claim 1, wherein said arterializing stent is from about 1 cm to about 4 cm in length.

17. The two-piece stent combination according to claim 1, wherein a cross section of said arterializing stent tapers from the trailing end to the leading end.

18. The two-piece stent combination according to claim 17, wherein said trailing end of said arterializing end is from about 4 mm to about 6 mm in diameter and said leading end of said arterializing stent is from about 2 mm to about 5 mm in diameter.

19. The two-piece stent combination according to claim 1, wherein said arterializing stent has a constant cross section.

20. The two-piece stent combination according to claim 19, wherein said arterializing stent is from about 1 mm to about 6 mm in diameter.

21. The two-piece stent combination according to claim 1, wherein said restricting covered stent is from about 1 mm to about 15 mm in diameter.

22. The two-piece stent combination according to claim 1, wherein said constriction of said restriction covered stent is from about 1 mm to about 6 mm in diameter.

23. The two-piece stent combination according to claim 1, wherein said arterializing stent and said restricting covered stent are of mesh construction.

24. The two-piece stent combination according to claim 1, wherein said arterializing stent and said restricting covered stent are of coiled construction.

25. The two-piece stent combination according to claim 1, wherein said arterializing stent and said restricting covered stent are connected.

26. The two-piece stent combination according to claim 2, wherein said right atrial proximal end of said restricting covered stent is positioned within the right atrium.

27. A method for retrogradely supplying oxygenated blood from a left ventricle to heart tissue via a coronary sinus comprising:

puncturing a hole through said coronary sinus and a wall of said left ventricle,

delivering an arterializing stent through said hole, wherein a leading end is placed in said left ventricle and a trailing end is placed in said coronary sinus,

and delivering a restricting covered stent with a coronary sinus distal end positioned within said coronary sinus.

28. The method according to claim 27, wherein said arterializing stent and said restricting covered stent are delivered percutaneously.

29. The method according to claim 27, further comprising expanding said arterializing stent after delivery within the hole.

30. The method according to claim 27, wherein said constriction of said restricting covered stent is positioned to fit approximately within a coronary ostium.

31. The method according to claim 27, wherein said right atrial end of said restricting covered stent is positioned within a right atrium.

32. The method according to claim 27, wherein said constriction and said right atrial end of said restricting covered stent are positioned within the coronary sinus.

33. The method according to claim 27, wherein said arterializing stent is appropriately sized to control blood flow from said left ventricle into said coronary sinus.

34. The method according to claim 27, wherein said restricting covered stent tapers toward said constriction and is appropriately sized to control blood flow from said coronary sinus into a right atrium.

35. The method according to claim 27, wherein a cross section at said constriction of said restricting covered stent and a cross section at said arterializing stent are appropriately sized to keep pressure inside the coronary sinus from rising above about 50 mm Hg while avoiding excessive left-to-right shunting.

36. The method according to claim 27, wherein a cross sectional at said constriction of said restricting covered stent and a cross section at said arterializing stent are appropriately sized to keep the pressure inside the coronary sinus from rising above about half the systemic pressure.