Retrograde venous perfusion with isolation of cerebral circulation
First Claim
1. A method for retrograde venous perfusion, comprising the steps of:
- providing a catheter having a proximal end and a distal end that branches into first and second distal segments, each distal segment having a lumen and a distal region having an expandable occluder and an infusion port located distal the occluder, the catheter further comprising a lumen extending from the proximal end and communicating with the lumen and infusion port of the first distal segment and the lumen and infusion port of the second distal segment;
inserting the first distal segment into a first internal jugular vein;
expanding the occluder on the first distal segment within the first internal jugular vein;
inserting the second distal segment into a second internal jugular vein;
expanding the occluder on the second distal segment within the second internal jugular vein;
inserting the proximal end of the catheter into the right subclavian vein;
withdrawing blood from the right subclavian vein;
oxygenating the withdrawn blood; and
infusing oxygenated medium into the first and second internal jugular veins through the lumens and infusion ports of the first and second distal segments, wherein oxygenated medium is returned to the cerebral tissues by retrograde venous perfusion.
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Accused Products
Abstract
A medical device for providing retrograde venous perfusion to the cerebral vasculature for treatment of global or focal cerebral ischemia is disclosed. The device includes a catheter having an infusion port at its distal end, venous drainage port(s), and an expandable occluder disposed between the infusion port and drainage port(s). The catheter can be inserted into the superior vena cava or the internal jugular vein. The catheter is attached proximally to a pump and an oxygenator with or without a cooling system. Alternatively, the device includes two catheters, each having a lumen communicating with a distal infusion port and an occluder mounted proximal to the port. The catheters can be inserted into the internal jugular veins distal to jugular venous valves. Methods of using the devices to provide retrograde venous perfusion and isolated cerebral hypothermia are disclosed.
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Citations
10 Claims
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1. A method for retrograde venous perfusion, comprising the steps of:
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providing a catheter having a proximal end and a distal end that branches into first and second distal segments, each distal segment having a lumen and a distal region having an expandable occluder and an infusion port located distal the occluder, the catheter further comprising a lumen extending from the proximal end and communicating with the lumen and infusion port of the first distal segment and the lumen and infusion port of the second distal segment;
inserting the first distal segment into a first internal jugular vein;
expanding the occluder on the first distal segment within the first internal jugular vein;
inserting the second distal segment into a second internal jugular vein;
expanding the occluder on the second distal segment within the second internal jugular vein;
inserting the proximal end of the catheter into the right subclavian vein;
withdrawing blood from the right subclavian vein;
oxygenating the withdrawn blood; and
infusing oxygenated medium into the first and second internal jugular veins through the lumens and infusion ports of the first and second distal segments, wherein oxygenated medium is returned to the cerebral tissues by retrograde venous perfusion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification