Stent for treating vulnerable plaque

• US 6,899,729 B1
• Filed: 12/18/2002
• Issued: 05/31/2005
• Est. Priority Date: 12/18/2002
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Cox, Daniel L., Feezor, Christopher
• Primary Examiner(s): McDermott, Corrine
• Assistant Examiner(s): SWEET, THOMAS
• Application Number:
  US10/322,350
• Time in Patent Office: 895 Days
• Field of Search: 623/1.13, 623/1.14, 623/1.15, 623/1.16, 623/1.17, 623/1.31, 623/1.3, 623/1.1, 606/200
• US Class Current: 623/1.13
• CPC Class Codes: A61B 5/6862 Stents
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0036 differing in thickness
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability

Abstract

An intravascular stent is configured for asymmetrical differential deployment and to align with a fibrous cap to treat vulnerable plaque. The stent is configured so that reduced expansion forces are imparted during deployment to the fibrous cap, thereby reducing the likelihood of cap rupture. The stent includes cylindrical rings connected by links and a cover attached to a portion of the stent to differentially restrict stent expansion when the stent is expanded from a delivery diameter to an implanted diameter thereby creating asymmetrical circumferential deployment. The portion of the stent having the cover imparts lower expansion forces from the stent expansion onto the fibrous cap area than other portions of the stent not having the cover.

Claims

1. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a tubular member having a distal end, a proximal end, and an outer surface and an inner surface extending therebetween to form the stent;

a cover having a length, an arc segment, and a radial thickness;

the cover being attached to a portion of the outer surface so that as the stent expands from a first delivery diameter to a second implanted diameter the cover differentially restricts stent expansion creating asymmetrical circumferential deployment; and

wherein the length of the cover is equal to the length of the stent.

2. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a tubular member having a distal end, a proximal end, and an outer surface and an inner surface extending therebetween to form the stent;

a cover having a length, an arc segment, and a radial thickness;

the cover being attached to a portion of the outer surface so that as the stent expands from a first delivery diameter to a second implanted diameter the cover differentially restricts stent expansion creating asymmetrical circumferential deployment; and

the stent includes a plurality of rings connected together by links and the stent rings and links have a variable radial thickness; and

wherein the cover has a variable thickness that mirrors the variable thickness of the stent rings and links providing a smooth outer surface along an outer surface of the stent cover.

3. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a tubular member having a distal end, a proximal end, and an outer surface and an inner surface extending therebetween to form the stent;

a cover having a length, an arc segment, and a radial thickness;

the cover being attached to a portion of the outer surface so that as the stent expands from a first delivery diameter to a second implanted diameter the cover differentially restricts stent expansion creating asymmetrical circumferential deployment; and

wherein the cover contains a sensor to measure any of temperature, blood flow, and blood pressure.

4. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a tubular member having a distal end, a proximal end, and an outer surface and an inner surface extending therebetween to form the stent;

a cover having a length, an arc segment, and a radial thickness;

the cover being attached to a portion of the outer surface so that as the stent expands from a first delivery diameter to a second implanted diameter the cover differentially restricts stent expansion creating asymmetrical circumferential deployment; and

wherein the cover is formed from a metallic material taken from the group of materials consisting of stainless steel, tantalum, nickel-titanium, cobalt-chromium, titanium, platinum, and gold.

5. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a plurality of cylindrical rings aligned along a common longitudinal axis, each cylindrical ring having curves and bar-arms that form undulations;

a plurality of links for connecting adjacent cylindrical rings; and

a first section and a second section;

the rings and links in the first section having a higher material density relative to the rings and links in the second section so that as the stent is expanded from a first delivery diameter to a second implanted diameter, the higher density first section differentially restricts stent expansion creating asymmetrical circumferential deployment.

6. The stent of claim 5, wherein the links and the curves and the bar-arms of the rings in the first section have a width that is greater than the width of the links, the curves and the bar-arms of the rings of the second section.

7. The stent of claim 6, wherein the width of the links and the curves and the bar-arms of the rings of the first section are progressively wider moving from a first edge of the first section to a second edge of the first section.

8. The stent of claim 5, wherein the width of the links and the curves and the bar-arms of the rings of the first section are progressively shorter moving from a first edge of the first section to a second edge of the first section.

9. The stent of claim 5, wherein the radial thickness of the links and the curves and the bar-arms of the rings of the first section are progressively thicker moving from a first edge of the first section to a second edge of the first section.

10. The stent of claim 5, wherein the number of undulations per ring in the first section is greater than the number of undulations per ring in the second section.

11. The stent of claim 5, wherein the number of links per ring in the first section is greater than the number of links per ring in the second section.

12. The stent of claim 5, wherein a cover is attached to at least a portion of the rings of the first section.

13. The stent of claim 5, wherein the first section extends circumferentially along an arc segment of less than 180°

.

14. The stent of claim 5, wherein the first section extends for a length equal to the length of the stent.

15. The stent of claim 5, wherein the first segment extends for a length less then the length of the stent.

16. The stent of claim 5, wherein the curves are circumferentially spaced at uneven distances from one another.

17. The stent of claim 5, wherein at least one of the curves and bar arms has a different width than other curves and bar arms of the same ring.

18. The stent of claim 5, wherein at least one of the curves and bar arms has a different radial thickness than other curves and bar arms of the same ring.

19. The stent of claim 5, wherein each ring of the plurality of cylindrical rings has a pattern formed by the undulations, and each ring has the same pattern formed by the undulations.

20. The stent of claim 5, wherein each ring of the plurality of cylindrical rings has a pattern formed by the undulations, and at least two rings have the same pattern formed by the undulations.

21. The stent of claim 5, wherein each ring of the plurality of cylindrical rings has a pattern formed by the undulations, and at least two rings have the same pattern formed by the undulations, wherein the curves are circumferentially spaced at uneven distances from one another.

22. A method of expanding a stent to create asymmetrical circumferential deployment in a body lumen having a fibrous cap, comprising:

providing a stent having a plurality of cylindrical rings aligned along a common longitudinal axis, each ring having curves and bar-arms that form undulations, a plurality of links for connecting adjacent rings, and a first section and a second section;

the first section having a first radial force component and the second section having a second radial force component;

aligning the first section of the stent with the fibrous cap;

expanding the stent into contact with the body lumen so that the first section substantially apposes the fibrous cap and the second section apposes that portion of the body lumen away from the fibrous cap.

23. The method of claim 22, wherein the first radial force component is less than the second radial force component so that the radial force applied to the fibrous cap is less than the radial force applied to the body lumen away from the fibrous cap.

24. A stent for reinforcing a fibrous cap in a body lumen, comprising:

a tubular member having means for expanding from a first delivery diameter to a second implanted diameter;

means associated with the tubular member for creating asymmetrical circumferential deployment; and

wherein the means for creating asymmetrical differential deployment includes rings having short bar arms and rings having long bar arms, the short bar arms creating less expansion forces than the long bar arms when the stent is expanded.