Control solution for photometric analysis

• US 6,900,058 B2
• Filed: 03/11/2003
• Issued: 05/31/2005
• Est. Priority Date: 03/11/2003
• Status: Expired due to Fees

• Current Assignee: Ferraris Group, Inc.
• Original Assignee: Bionostics, Inc.
• Inventors: Murray, Donna M., Rafferty, Donna M., Rannikko, Minna A.
• Primary Examiner(s): Wallenhorst, Maureen M.
• Application Number:
  US10/387,115
• Publication Number:
  US 20040180444A1
• Time in Patent Office: 812 Days
• Field of Search: 436/8, 436 12- 16, 436/18, 436/164, 436/166, 436/800, 435/14, 252/408.1
• US Class Current: 436/14
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 2496/15 containing dyes to mimic optical absorption of, e.g. hemoglobin
• CPC Class Codes: G01N 2496/25 containing added polymers to stabilise biological material against degradation or mantain viscosity or density, e.g. gelatin, polyacrylamides, polyvinyl alcohol casein G01N2333/4731, albumins G01N2333/76, polysaccharides G01N2400/10
• CPC Class Codes: G01N 2496/35 Polyvinylpyrrolidone, e.g. PVP
• CPC Class Codes: G01N 2496/80 Multi-analyte reference solutions containing cholesterol, glucose and the like
• CPC Class Codes: G01N 33/96 involving blood or serum control standard
• CPC Class Codes: Y10T 436/10 Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
• CPC Class Codes: Y10T 436/104998 Glucose, ketone, nitrate standard or control
• CPC Class Codes: Y10T 436/105831 Protein or peptide standard or control [e.g., hemoglobin, etc.]
• CPC Class Codes: Y10T 436/106664 Blood serum or blood plasma standard or control
• CPC Class Codes: Y10T 436/108331 Preservative, buffer, anticoagulant or diluent

Abstract

An aqueous control solution is disclosed for use with a spectrophotometer or photometric test strip that includes a predetermined amount of an analyte, a hydrophobic reference dye and a surfactant. In one embodiment, the aqueous control solution is applied to a photometric test strip having a chemical that oxidizes glucose and consequently forms hydrogen peroxide which reacts with an indicator dye that is also present on the strip. In this embodiment, the control solution includes a predetermined amount of glucose, an infrared reference dye, sodium dodecyl sulfate, and the indicator dye, such as sulforhodamine B.

Claims

1. An aqueous control solution, comprising a predetermined amount of glucose, C₆₂H₉₆N₆SbF₆, sodium dodecyl sulfate, and an indicator dye selected from the group consisting of sulforhodamine B and rose bengal.

2. The solution of claim 1, further comprising a preservative.

3. The solution of claim 2, wherein the preservative is selected from the group consisting of diazolidinyl urea, sodium benzoate, potassium benzoate, benzalkonium chloride, chlorhexidine, imidazolidinyl urea, 5-chloro-2-methyl-4-isothiazolinone, 2-methyl-4-isothiazoline-3-one and mixtures thereof.

4. The solution of claim 3, wherein the preservative is diazolidinyl urea or a mixture of 5-chloro-2-methyl-4-isothiazolin-one and 2-methyl-4-isothiazoline-3-one.

5. The solution of claim 1, further comprising a buffer.

6. The solution of claim 5, wherein the buffer is selected from the group consisting of a citrate buffer, an imidazole buffer and a N-2-hydroxyethyl piperazine-N-2-ethanesulfonic acid buffer.

7. The solution of claim 1, further comprising a viscosity enhancer.

8. The solution of claim 7, wherein the viscosity enhancer is glycerol, polyvinylpyrrolidone or a combination thereof.

9. The solution of claim 1, further comprising:

a) a citrate buffer or a N-2-hydroxyethyl piperazine-N-2-ethanesulfonic acid buffer;

b) glycerol, polyvinylpyrrolidone, or a combination thereof; and

c) diazolidinyl urea, or a combination of 5-chloro-2-methyl4-isothiazolin-one and 2-methyl-4-isothiazoline-3-one.