Distinguishing valid and invalid cardiac senses

• US 6,901,291 B2
• Filed: 11/28/2001
• Issued: 05/31/2005
• Est. Priority Date: 12/04/2000
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Rouw, Mattias, Stoop, Gustaaf A. P., Van Dam, Peter
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US09/994,873
• Publication Number:
  US 20020128688A1
• Time in Patent Office: 1,280 Days
• Field of Search: 607/4, 607/5, 607/9, 607 11- 14, 607/27, 607/28, 128/898
• US Class Current: 607/27
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

Systems and methods for distinguishing a valid sensed cardiac signal from an invalid signal, such as a myopotential. In one embodiment, sensing an electrical signal with one electrode causes a timing window to commence. When the electrical signal is sensed by another electrode in the timing window, the sense is deemed valid. When the electrical signal is not sensed by the other electrode in the timing window, the sense is deemed invalid. Therapy may be adjusted when an inordinate number of senses are invalid.

Claims

1. A method comprising:

sensing an electrical signal with a first electrode;

commencing a timing window;

inhibiting delivery of a pacing therapy by the first electrode subsequent to termination of an escape interval during the timing window; and

recording the electrical signal as an invalid sense when a second electrode fails to sense the electrical signal in the timing window.

2. A method of claim 1, further comprising:

ending the timing window; and

resetting an escape interval when the second electrode senses the electrical signal in the timing window.

3. The method of claim 2, wherein the second electrode senses the electrical signal in the timing window.

4. The method of claim 1, wherein the first electrode is the a left ventricular electrode and the second electrode is a right ventricular electrode.

5. The method claim 1, further comprising:

performing a morphological analysis of the electrical signal; and

recording the electrical signal as an invalid sense as a function of the morphological analysis.

6. The method of claim 1, further comprising counting the number of invalid senses during a monitoring period.

7. The method of claim 6, further comprising adjusting therapy as a function of the number of invalid senses during the monitoring period.

8. The method of claim 1, wherein inhibiting delivery of a pacing therapy comprises:

determining whether termination of the escape interval occurs a predetermined time period prior to expiration of the timing window;

inhibiting delivery of the pacing therapy in response to termination of the escape interval occurring within the predetermined time period; and

delivering the pacing therapy in response to termination of the escape interval not occurring within the predetermined time period.

9. A computer-readable medium comprising instructions for causing a programmable processor to:

sense a electrical signal with a first electrode;

commence a timing window;

inhibit delivery of a pacing therapy by the first electrode subsequent to termination of an escape interval during the timing window; and

record the electrical signal as an invalid sense when a second electrode fails to sense the electrical signal in the timing window.

10. The medium of claim 9, the instructions further causing the programmable processor to:

end the timing window; and

reset an escape window when the second electrode senses the electrical signal in the timing window.

11. The medium of claim 10, wherein the second electrode delivers pacing therapy, the instructions further causing the programmable processor to inhibit pacing therapy with the second electrode until the expiration of the reset escape interval.

12. The medium of claim 9, wherein the first electrode is a left ventricular electrode and the second electrode is a right ventricular electrode.

13. The medium of claim 9, the instructions further causing the programmable processor to:

perform a morphological analysis of the electrical signal; and

record the electrical signal as an invalid sense as a function of the morphological analysis.

14. The medium of claim 9, the instructions further causing the programmable processor to count the number of invalid senses during a monitoring period.

15. The medium of claim 14, the instructions further causing the programmable processor to adjust therapy as a function of the number of invalid senses during the monitoring period.

16. A method comprising:

sensing an electrical signal with a left ventricular electrode;

commencing a timing window;

inhibiting delivery of a pacing therapy by the left ventricular electrode subsequent to termination of an escape interval during the timing window; and

recording the electrical signal as an invalid sense when a right ventricular electrode fails to sense the electrical signal in the timing window.

17. The method of claim 16, further comprising:

sensing the electrical signal with the right ventricular electrode in the timing window;

ending the timing window;

resetting an escape interval; and

inhibiting pacing with the right ventricular electrode until the expiration of the reset escape interval.

18. The method of claim 16, further comprising ending the timing window and delivering a right ventricular pace when a ventricular escape interval expires in the timing window.

19. The method of claim 16, further comprising delivering a left ventricular pace and a right ventricular pace after the timing window expires.

20. The method claim 19, further comprising:

delivering the left ventricular pace immediately after the timing window expires.

21. A system comprising:

a first electrode for placement proximal to a heart;

a second electrode for placement proximal to the heart;

a controller that senses an electrical signal as an invalid sense when the controller fails to sense the electrical signal with the second electrode in a timing window, wherein the controller inhibits delivery of a pacing therapy by the first electrode subsequent to termination of an escape interval during the timing window.

22. The system of claim 21, wherein the controller ends the timing window and resets an escape interval when the controller senses the electrical signal with the second electrode in the timing window.

23. The system of claim 21, wherein the controller counts the number of invalid senses during a monitoring period.

24. The system of claim 23, wherein the controller adjusts therapy as a function of the number of invalid senses during the monitoring period.

25. The system of claim 21, wherein the controller performs a morphological analysis of the electrical signal.

26. The system of claim 21, wherein the first electrode is a left ventricular electrode and the second electrode is a right ventricular electrode.

27. The system of claim 26, wherein the controller delivers a right ventricular pace and a left ventricular pace after the timing window expires.

28. The system of claim 21, wherein the controller comprises a microprocessor.

29. The system of claim 21, wherein the controller determines whether termination of the escape interval occurs a predetermined time period prior to expiration of the timing window, inhibits delivery of the pacing therapy in response to termination of the escape interval occurring within the predetermined time period, and delivers the pacing therapy in response to termination of the escape interval not occurring within the predetermined time period.

30. A method comprising:

in a first monitoring period,

sensing at least one electrical signal with a first electrode,

commencing a timing window having a first duration and

recording the electrical signal as an invalid sense when a second electrode fails to sense the electrical signal in the timing window having the first duration; and

in a second monitoring period,

sensing at least one electrical signal with the first electrode,

commencing a timing window having a second duration.

31. The method of claim 30, further comprising recording the electrical signal as a valid sense in the first monitoring period when the second electrode senses the electrical signal in the timing window having the first duration.

32. The method claim 30, further comprising:

incrementing a counter for each electrical signal sensed with the first electrode in the first monitoring period.

33. The method of claim 32, further comprising:

resetting the counter;

incrementing the counter for each electrical signal sensed with the first electrode in the second monitoring period.

34. The method of claim 30, further comprising selecting a timing window duration as a function of the invalid senses in the first monitoring period and the second monitoring period.

35. A method comprising:

sensing an electrical signal with a first electrode;

commencing a timing window;

inhibiting delivery of a pacing therapy by the first electrode subsequent to termination of an escape interval during the timing window; and

recording the electrical signal as a valid sense when a second electrode senses the electrical signal in the timing window.

36. The method claim 35, further comprising recording the electrical signal as an invalid sense when a second electrode fails to sense the electrical signal in the timing window.

37. The method of claim 35, further comprising ending the timing window and resetting an escape interval when the second electrode senses the electrical signal in the timing window.

38. The method of claim 35, wherein the first electrode is a left ventricular electrode and the second electrode is a right ventricular electrode.

39. The method of claim 35, further comprising:

performing a morphological analysis of the electrical signal; and

recording the electrical signal as a valid sense as a function of the morphological analysis.

40. The method of claim 35, further comprising counting the number of total electrical signals sensed with the first electrode during a monitoring period.

41. A computer-readable medium comprising instructions for causing a programmable processor to:

sense an electrical signal with a first electrode;

commence a timing window;

inhibiting delivery of a pacing therapy by the first electrode subsequent to termination of an escape interval during the timing window; and

record the electrical signal as a valid sense when a second electrode senses the electrical signal in the timing window.

42. The medium of claim 41, the instructions further causing the programmable processor to record the electrical signal as an invalid sense when a second electrode fails to sense the electrical signal in the timing window.

43. The medium of claim 41, the instructions further causing the programmable processor to end the timing window and reset an escape interval when the second electrode senses the electrical signal in the timing window.

44. The medium of claim 41, wherein the first electrode is a left ventricular electrode and the second electrode is a right ventricular electrode.

45. The medium of claim 41, the instructions further causing the programmable processor to:

perform a morphological analysis of the electrical signal; and

record the electrical signal as a valid sense as a function of the morphological analysis.

46. The medium of claim 41, the instructions further causing the programmable processor to count the number of total electrical signals sensed with the first electrode during a monitoring period.

47. A system comprising:

a first sensing means for placement proximal to a heart;

a second sensing means for placement proximal to the heart;

a therapy delivery means for delivering therapy to the heart; and

a controlling means for sensing an electrical signal with the first sensing means, commencing a timing window, inhibiting delivery of a pacing therapy by the therapy delivery means subsequent to termination of an escape interval during the timing window, and recording the electrical signal as an invalid sense when the controller fails to sense the electrical signal with the second sensing means in the timing window.

48. The system of claim 47, wherein the controller means ends the timing window and resets an escape interval when the controller senses the electrical signal with the second sensing means in the timing window.

49. The system of claim 47, wherein the controller means counts the number of invalid senses during a monitoring period and adjusts therapy as a function of the number of invalid senses during the monitoring period.

50. The system of claim 47, wherein the controller means performs a morphological analysis of the electrical signal.

51. The system of claim 50, wherein the controller means includes a means for converting the electrical signal to a digital signal.

52. The system of claim 47, wherein the controller means comprises a microprocessor.

53. The system of claim 47, wherein the controller means comprises a sense amplifier means for providing a sensing threshold as a function of the measured amplitude of the electrical signal.