Oligomer for immobilizing physiological material, and composition for immobilizing physiological material comprising the same

• US 6,903,177 B2
• Filed: 12/23/2002
• Issued: 06/07/2005
• Est. Priority Date: 01/14/2002
• Status: Expired due to Fees

• Current Assignee: Samsung SDI Company Limited
• Original Assignee: Samsung SDI Company Limited
• Inventors: Seo, Kang-Il, Lee, In-Ho, Kim, Hun-Soo, Park, Tai-Jun
• Primary Examiner(s): PENG, KUO LIANG
• Application Number:
  US10/328,467
• Publication Number:
  US 20030153069A1
• Time in Patent Office: 897 Days
• Field of Search: 528/34, 528/38, 528/37, 106/287, 106/11, 427/387, 428/447
• US Class Current: 528/38
• CPC Class Codes: C07F 7/21 Cyclic compounds having at least one ring containing silicon, but no carbon in the ring
• CPC Class Codes: Y10T 428/31663 As siloxane, silicone or silane

Abstract

The present invention provides a silane oligomer for immobilizing a physiological material that is prepared by copolymerizing an aminosilane compound with a cyclic siloxane oligomeric compound. The present invention can preserve the immobilization layer by applying a silane oligomer. Further, the immobilization layer has a three-dimensional structure and thus has superior thermal stability and reagent resistance.

Claims

1. A silane oligomer for immobilizing a physiological material that is prepared by copolymerizing an aminosilane compound represented by the following formula (1) with a cyclic siloxane oligomeric compound represented by the following formula (2):

H₂N—

R²—

Si(R¹)₃ 

 

(1)

2. The silane oligomer according to claim 1, wherein the aminosilane compound of formula (1) and the cyclic siloxane oligomeric compound of formula (2) are provided in a mixed ratio of 0.01:

99.99 to 90;

10.

3. The silane oligomer according to claim 1, wherein the aminosilane compound of formula (1) is selected from the group consisting of 3-aminopropyltrimethoxysilane, 3-aminopropyltriethoxysilane, 2-aminoundecyltrimethoxysilane, aminophenyltrimethoxy-silane, N-(2-aminoethylaminopropyl)trimethoxysilane, and combinations thereof.

4. The silane oligomer according to claim 1, wherein the compound of formula (2) is a cyclic methylsiloxane oligomeric compound.

5. A method for preparing an oligomer, comprising:

mixing an aminosilane compound represented by the following formula (1) with a cyclic siloxane oligomeric compound represented by the following formula (2)

H₂N—

R²—

Si(R¹)₃ 

 

(1)

6. The method for preparing an oligomer according to claim 5, wherein the method further comprises adjusting the pH of the aqueous solution from 4 to 10 before the copolymerization reaction.