Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device

• US 6,905,509 B2
• Filed: 07/18/2001
• Issued: 06/14/2005
• Est. Priority Date: 01/23/1998
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Innercool therapies Incorporated (Taxus Cardium Pharmaceuticals Group, Inc.)
• Inventors: Lasheras, Juan C., Werneth, Randell L., Dobak, John D. III
• Primary Examiner(s): Rollins, Rosiland
• Application Number:
  US09/908,642
• Publication Number:
  US 20020032474A1
• Time in Patent Office: 1,427 Days
• Field of Search: 607/96, 607104-112, 607/113, 607/114, 607/115, 606 27- 32
• US Class Current: 607/96
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2018/0262 using a circulating cryogenic fluid
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: G05D 23/1919 characterised by the type of controller
• CPC Class Codes: G05D 23/22 the sensing element being a thermocouple
• CPC Class Codes: G05D 23/24 the sensing element having a resistance varying with temperature, e.g. a thermistor

Abstract

A catheter and method are provided for modifying a temperature of a patient. The catheter includes a heat transfer element (“HTE”) having surface irregularities shaped to create turbulence in a surrounding fluid. The catheter also includes a supply catheter to deliver a working fluid to an interior of the heat transfer element and a return catheter to return a working fluid from the HTE. A guidewire lumen is provided to receive a guidewire. The guidewire may have a temperature-monitoring device disposed at its distal tip from which feedback may be provided to control the temperature of a source of the working fluid.

Claims

1. A temperature monitoring device assembly, comprising:

an elongated heat exchange catheter having a distal end and a proximal end, the catheter being configured for advancing the catheter into the venous system of a patient, along a path defined by a guidewire, with the distal end located in the patient'"'"'s body and the proximal end located outside the patient'"'"'s body;

at least one temperature monitoring device, located at or near the distal end of the guidewire, generating respective at least one temperature signal, the distal end of the guidewire and temperature monitoring device, located distal if the distal end of the catheter;

a catheter connector located at or near the proximal end or the catheter;

a heat exchanger;

at least One controller; and

a cable having a cable connector configured for engaging the catheter connector and the at least one controller electrically connected to the cable connector,

wherein the temperature monitoring device generates a control feedback signal useful by the controller for controlling the heat exchanger, and

wherein the catheter is in closed loop fluid communication with the heat exchanger such that a working fluid, the temperature of which is controlled based on the control feedback signal, is provided to the catheter from the heat exchanger to alter the temperature of fluid surrounding the catheter, such that the distal location of the temperature monitoring device causes the temperature monitoring device to sense the temperature of a given volume of blood closer to the heart of the patient, wherein a more accurate indication of core body temperature is achieved.

2. The probe of claim 1, wherein the catheter is configured for advancement into a patient'"'"'s vasculature.

3. The assembly of claim 1, wherein the temperature monitoring device includes a thermistor and the probe body is disposable.