Speech processing system and method using pseudospontaneous stimulation

• US 6,907,130 B1
• Filed: 02/13/1998
• Issued: 06/14/2005
• Est. Priority Date: 02/13/1998
• Status: Expired due to Fees

• Current Assignee: Research Triangle Institute, University of Iowa Research Foundation
• Original Assignee: Research Triangle Institute, University of Iowa Research Foundation
• Inventors: Wilson, Blake, Rubinstein, Jay
• Primary Examiner(s): Kuntz, Curtis
• Assistant Examiner(s): Harvey, Dionne
• Application Number:
  US09/023,279
• Time in Patent Office: 2,678 Days
• Field of Search: 607 55- 57, 607/137, 600/25, 381/326, 381/331, 381/151, 381/312, 381/320, 381/316, 381/FOR.130, 623/10, 455/40, 455/41, 455/43
• US Class Current: 381/312
• CPC Class Codes: A61N 1/36038 Cochlear stimulation

Abstract

A apparatus and method for inner ear implants is provided that generates signal processing stochastic independence activity across the excited neural population. A high rate pulse train can produce random spike patterns in auditory nerve fibers (hereafter “pseudospontaneous activity”) that are statistically similar to those produced by spontaneous activity in the normal auditory nerve. We call this activity “pseudospontaneous”. Varying rates of pseudospontaneous activity can be created by varying the intensity of a fixed amplitude, high rate pulse train stimulus, e.g., 5000 pps. The high rate pulse train can desynchronize the nerve fiber population and can be combined with a data signal in an inner ear implant. The pseudospontaneous activity can enhance neural representation of temporal detail and dynamic range with an inner ear implant such as a cochlear implant. The pseudospontaneous activity can further eliminate a major difference between acoustic-and electrical-derived hearing percepts.

Claims

1. A cochlear system, comprising:

a signal generator that generates a second signal capable of causing pseudospontaneous activity in an auditory nerve;

a signal processor that combines a first signal that represents sound and the second signal to output a combined signal; and

a stimulation unit coupled to the signal processor that receives the combined signal from the signal processor, wherein the stimulation unit is configured to apply the combined signal to the auditory nerve.

2. The system according to claim 1, wherein the stimulation unit is an electrode array unit that is coupled to the auditory nerve.

3. The system according to claim 2, wherein the first signal is applied to a first subset of electrodes in the electrode array and the second signal is applied to a second subset of electrodes in the electrode array.

4. The system according to claim 1, wherein the second signal includes one of (i) a pulse train generating substantially continuous pseudospontaneous activity, (ii) a broad band noise, and (iii) at least fluctuations in amplitude greater than prescribed amount at a frequency above approximately 2 k Hz that causes statistically independent activity in a plurality of nerve fibers of the nerve.

5. The system according to claim 1, wherein the pseudospontaneous activity is demonstrated by statistically independent activity in a plurality of nerve fibers in the auditory nerve.

6. The system according to claim 1, wherein the second signal includes rapid state transitions and a frequency greater than approximately 3 kilohertz.

7. The system according to claim 1, wherein the signal processor determines the combined signal by summing the first and second signals.

8. The system according to claim 1, further comprising a microphone that generates the first signal, wherein the microphone is coupled to the signal processor.

9. The system according to claim 1, wherein the signal processor further comprises a combining circuit that logically processes the first and second signals, wherein the combining circuit ANDs the first and second signals.

10. The system according to claim 1, wherein a microphone, the signal processor and the signal generator are positioned external to an ear, wherein the stimulation unit is coupled by a wire to the signal processor, and wherein the stimulation unit is coupled to the auditory nerve via a cochlea.

11. A method for generating a driving signal for an auditory implant, comprising:

receiving a first signal;

generating a second signal that causes pseudo-spontaneous activity in an acoustic nerve;

combining the first and second signals to generate the driving signal; and

applying the combined signal to the acoustic nerve.

12. The method according to claim 11, wherein the first signal represents at least one of speech, emergency signals and control information.

13. The method according to claim 11, wherein the combining step performs at least one of summing and multiplying the first and second signals.

14. The method of claim 11, wherein the applying the combined signal generates substantially continuous pseudospontaneous activity.

15. The method of claim 11, wherein the second signal is not continuously applied.

16. The method of claim 11, wherein the second signal includes one of (i) a pulse train generating substantially continuous pseudospontaneous activity, (ii) a broad band noise, and (iii) at least fluctuations in amplitude greater than prescribed amount at a frequency above approximately 2 k Hz that causes statistically independent activity in a plurality of nerve fibers of the nerve, wherein the driving signal is used to modulate a carrier signal.

17. An auditory prosthesis for receiving an auditory signal representing sound and supplying an electrical signal which is adapted to stimulate the auditory nerve of a person, comprising:

pseudospontaneous generation means for generating a pseudospontaneous driving signal;

transducer means adapted to receive the auditory signal and the pseudospontaneous driving signal for transforming the auditory signal and the pseudospontaneous driving signal to electrical input signals; and

stimulation means, operatively coupled to the electrical input signals generated by the transducer means, for stimulating the auditory nerve at defined locations within the cochlea, wherein at least one of the plurality of electrical signals is configured to cause statistically independent activity in a plurality of nerve fibers of an auditory nerve.

18. The auditory prosthesis of claim 17, wherein the transducer means further performs at least one of the summing and multiplying the auditory signal and the pseudo-spontaneous driving signal.

19. The auditory prosthesis of claim 17, wherein the pseudospontaneous driving signal includes one of (i) a pulse train generating substantially continuous activation, (ii) a broad band noise, or (iii) at least fluctuations in amplitude greater than prescribed amount at a frequency above approximately 2 k Hz, wherein the electrical signals stimulate the auditory nerve.

20. A neural prosthetic apparatus, comprising.

a signal generator that generates a second signal;

a signal processor that combines a first signal that represents sound and the second signal to output a combined signal, wherein a carrier signal is modulated with the combined signal; and

stimulation unit coupled to the signal processor that receives and demodulates the carrier signal to obtain the combined signal from the signal processor for application to the auditory nerve, wherein the second signal includes at least fluctuations in amplitude greater than a prescribed amount at a frequency above approximately 2 kHz.

21. The apparatus according to claim 20, wherein the stimulation unit is an electrode array unit that is coupled to the auditory nerve, and wherein the first signal is applied to a first subset of electrodes in the electrode array and the second signal is applied to a second subset of electrodes in the electrode array.

22. The apparatus according to claim 20, wherein the second signal generates statistically independent activity in a plurality of nerve fibers in the auditory nerve.

23. The apparatus according to claim 20, wherein the auditory nerve comprises a plurality of nerve fibers, and wherein the second signal comprises one or more signals that generate a substantially maximum firing rate of the plurality of nerve fibers.

24. The apparatus according to claim 20, wherein the second signal includes one of (i) a pulse train generating substantially continuous pseudospontaneous activity being statistically independent activity in a plurality of nerve fibers of the nerve, and (ii) a broad band noise that causes statistically independent activity in the plurality of nerve fibers of the nerve.

25. The apparatus according to claim 20, wherein the prosthesis is a cochlear implant applying current to the auditory nerve, wherein the stimulation unit is configured to apply the combined signal to the auditory nerve.

26. The apparatus according to claim 20, wherein the pseudospontaneous activity continues after the second signal is stopped.

27. A method of modifying a neural prosthetic apparatus that receives an information signal and supplies a corresponding electrical signal to stimulate an auditory nerve, comprising:

providing a pseudospontaneous signal generator that generates a second signal; and

providing an electrical coupling means for supporting an electrical connection from the pseudospontaneous signal generator to at least one electrical contact, and wherein the second signal is configured to induce a random pattern of activation in the auditory nerve mimicking the spontaneous neural activity of the auditory nerve.

28. The method of claim 27, wherein the information signal represents at least one of speech, emergency signals and control information, and wherein the second signal includes one of (i) a pulse train generating substantially continuous pseudospontaneous activity, (ii) a broad band noise, (iii) at least fluctuations in amplitude greater than prescribed amount at a frequency above approximately 2 k Hz, and (iv) at least fluctuations in amplitude greater than prescribed amount at a frequency that causes statistically independent activity in a plurality of nerve fibers of the auditory nerve.

29. The method of claim 27, wherein the neural prosthetic apparatus is a cochlear implant, wherein the second signal and the electrical signal are used to modulate a carrier signal.