Human kinase proteins and polynucleotides encoding the same

• US 6,908,758 B2
• Filed: 07/15/2003
• Issued: 06/21/2005
• Est. Priority Date: 04/25/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Hu, Yi, Donoho, Gregory, Wang, Xiaoming, Scoville, John, Walke, D. Wade, Nepomnichy, Boris
• Primary Examiner(s): Monshipouri, Maryam
• Application Number:
  US10/620,845
• Publication Number:
  US 20040115693A1
• Time in Patent Office: 707 Days
• Field of Search: 536/23.2, 435/194, 435/320.1, 435/325, 435/252.3, 435/6
• US Class Current: 435/252.3
• CPC Class Codes: C12N 9/12 transferring phosphorus containing groups, e.g. kinases (2.7)
• CPC Class Codes: C12N 9/1205 Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

9; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

8 or the complement thereof.

2. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

9.

3. An isolated nucleic acid molecule comprising the nucleotide sequence shown in SEQ ID NO:

8.

4. A recombinant expression vector comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

9.

5. The recombinant expression vector of claim 4 wherein said nucleotide sequence is that shown in SEQ ID NO:

8.

6. A host cell comprising the vector of claim 4.

7. A host cell comprising the vector of claim 5.