Cosmetic repair using cartilage producing cells and medical implants coated therewith

• US 6,911,202 B2
• Filed: 02/06/2002
• Issued: 06/28/2005
• Est. Priority Date: 02/06/2001
• Status: Active Grant

• Current Assignee: Abraham Amir, Reva Amir
• Original Assignee: Abraham Amir, Reva Amir
• Inventors: Amir, Abraham, Amir, Reva
• Primary Examiner(s): Coe, Susan D.
• Application Number:
  US10/066,753
• Publication Number:
  US 20020106352A1
• Time in Patent Office: 1,238 Days
• Field of Search: 424/93.7, 424/401
• US Class Current: 424/93.7
• CPC Class Codes: A61K 35/12 Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells vaccines or medicinal preparations containing antigens or antibodies A61K39/00
• CPC Class Codes: A61L 27/3817 Cartilage-forming cells, e.g. pre-chondrocytes
• CPC Class Codes: C12N 2500/32 Amino acids
• CPC Class Codes: C12N 5/0655 Chondrocytes; Cartilage

Abstract

A method of cosmetically repairing a skin contour irregularity in a subject is provided. The method is effected by introducing cartilage producing cells into the skin contour irregularity thereby effecting cosmetic repair thereof. A medical implant coated with cartilage producing cells is further disclosed.

Claims

1. A method of cosmetically repairing a skin contour irregularity in a subject, the method comprising introducing a support free suspension of cultured isolated cartilage-producing cells devoid of solid particles into the skin contour irregularity thereby effecting cosmetic repair thereof.

2. The method of claim 1, wherein said cartilage producing cells are selected from the group consisting of chondrocytes and chondrocyte progenitor cells.

3. The method of claim 1, wherein said cartilage producing cells are harvested from the subject.

4. The method of claim 1, wherein said cartilage producing cells are harvested from a source syngeneic with respect to the subject.

5. The method of claim 1, wherein said cartilage producing cells are harvested from a source allogeneic with respect to the subject.

6. The method of claim 1, wherein the skin contour irregularity is selected from the group consisting of a rhytid, a subcutaneous defect and a depression.

7. The method of claim 1, wherein said introducing is effected via subcutaneous injection.