Hormone replacement formulation
First Claim
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1. An estrogen formulation for use in hormone replacement therapy, comprising:
- a combination of three estrogens, the combination including an amount of 2-hydroxyestrone, an amount of 17-beta estradiol, and an amount of estriol, wherein the amounts of 2-hydroxyestrone and estriol are approximately equal and wherein each comprise approximately 35%-45% by weight of the three estrogens, and wherein the 17-beta estradiol comprises the remainder of the three estrogen combination.
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Abstract
The formulation comprises a combination of three estrogens and selected amount of other elements. The three estrogens include 2-hydroxyestrone, 17-beta estradiol, and estriol. The amount of 17-beta estradiol is substantially less than the amounts of 2-hydroxyestrone and estriol, both which are approximately equal in amount. The amounts of pyridoxine, folic acid, selenium and cobalt are therapeutically effective amounts.
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Citations
7 Claims
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1. An estrogen formulation for use in hormone replacement therapy, comprising:
a combination of three estrogens, the combination including an amount of 2-hydroxyestrone, an amount of 17-beta estradiol, and an amount of estriol, wherein the amounts of 2-hydroxyestrone and estriol are approximately equal and wherein each comprise approximately 35%-45% by weight of the three estrogens, and wherein the 17-beta estradiol comprises the remainder of the three estrogen combination. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An estrogen formulation for use in hormone replacement therapy, comprising:
a combination of two estrogens, the combination including an amount of 2-hydroxyestrone and an amount of 17-beta estradiol, wherein the formulation comprises 80-90% of 2-hydroxyestrone and 10-20% of 17-beta estradiol.
Specification