Device and method for enhancing transdermal agent flux
First Claim
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1. A method for introducing an agent through a body surface, comprising the steps of:
- providing a member having a body surface proximal side, a body surface distal side, a first surface on the body surface proximal side of the member and a second-surface distal side of the member;
said member having a plurality of protrusions extending from the first surface and extending towards the body surface and a connecting medium disposed on at least a portion of the first surface;
introducing the agent in the connecting medium;
piercing the body surface with the plurality of protrusions extending from the first surface of the member;
contacting the body surface with the connecting medium; and
passing the agent through the body surface.
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Abstract
An agent delivery or sampling device (2) comprising a member (6) having a plurality of blades (4) for piercing the skin and a connecting medium (65) covering at least a part of the skin contacting side (48) of the member (6) for increasing transdermal flux of an agent.
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Citations
6 Claims
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1. A method for introducing an agent through a body surface, comprising the steps of:
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providing a member having a body surface proximal side, a body surface distal side, a first surface on the body surface proximal side of the member and a second-surface distal side of the member;
said member having a plurality of protrusions extending from the first surface and extending towards the body surface and a connecting medium disposed on at least a portion of the first surface;introducing the agent in the connecting medium; piercing the body surface with the plurality of protrusions extending from the first surface of the member; contacting the body surface with the connecting medium; and passing the agent through the body surface. - View Dependent Claims (2)
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3. A method for withdrawing an agent through a body surface, comprising the steps of:
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piercing the body surface with a plurality of protrusions extending from a body surface proximal side of a member having a connecting medium capable of passing the agent therethrough, the connecting medium disposed on at least a portion of the body surface proximal side; contacting the body surface with the connecting medium; and withdrawing the agent through the body surface. - View Dependent Claims (4)
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5. A device for introducing or withdrawing an agent through a body surface, comprising:
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a member having a body surface proximal side, a body surface distal side and a plurality of protrusions extending from said body surface proximal side; a connecting medium capable of storing the agent therein or passing the agent therethrough on at least a portion of the body surface proximal side of the member; and a sampling device connected to the body surface distal side, the sampling device selected from the group consisting of a reverse osmosis device, an electrotransport device, a passive device and an osmotic device.
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6. A device for introducing or withdrawing an agent through a body surface, comprising:
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a member having a body surface proximal side, a body surface distal side and a plurality of protrusions extending from said body surface proximal side;
said member further having at least one hole through the member;a connecting medium capable of storing the agent therein or passing the agent therethrough on at least a portion of the body surface proximal side of the member; and a sampling device connected to the body surface distal side, the sampling device selected from the group consisting of a reverse osmosis device, an electrotransport device, a passive device and an osmotic device.
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Specification