Microfluidic analytical devices and methods
First Claim
Patent Images
1. A microfluidic device for passively mixing at least two fluids for analysis, the device comprising a plurality of device layers defining:
- a first fluidic input;
a first junction or manifold region in fluid communication with the first fluidic input;
a first plurality of unequal impedance branch channels in fluid communication with the first junction or manifold region;
a second fluidic input;
a second junction or manifold region in fluid communication with the second fluidic input;
a second plurality of unequal impedance branch channels in fluid communication with the second junction or manifold region;
a plurality of mixer regions in fluid communication with the first plurality of unequal impedance branch channels and the second plurality of unequal impedance branch channels, wherein the plurality of mixer regions, the first plurality of unequal impedance branch channels, and the second plurality of unequal impedance branch channels are disposed within the plurality of device layers so as to permit simultaneous and combination of a first fluid and a second fluid in a plurality of different predetermined mixing ratios; and
a detection region in fluid communication with the plurality of mixer regions.
2 Assignments
0 Petitions
Accused Products
Abstract
Modular microfluidic systems includes a plurality of microfluidic modules, each capable of performing fluidic operations including, but not limited to, filtering, splitting, regulating pressure, mixing, metering, reacting, diverting, heating, cooling, and condensing are provided. The microfluidic modules are polymeric, stencil-based structures adapted to be coupled in sequence for performing biological or chemical synthesis, including, but not limited to, chemical and biological syntheses of organic, polymer, inorganic, oligonucleotide, peptide, protein, bacteria, and enzymatic products.
-
Citations
14 Claims
-
1. A microfluidic device for passively mixing at least two fluids for analysis, the device comprising a plurality of device layers defining:
-
a first fluidic input;
a first junction or manifold region in fluid communication with the first fluidic input;
a first plurality of unequal impedance branch channels in fluid communication with the first junction or manifold region;
a second fluidic input;
a second junction or manifold region in fluid communication with the second fluidic input;
a second plurality of unequal impedance branch channels in fluid communication with the second junction or manifold region;
a plurality of mixer regions in fluid communication with the first plurality of unequal impedance branch channels and the second plurality of unequal impedance branch channels, wherein the plurality of mixer regions, the first plurality of unequal impedance branch channels, and the second plurality of unequal impedance branch channels are disposed within the plurality of device layers so as to permit simultaneous and combination of a first fluid and a second fluid in a plurality of different predetermined mixing ratios; and
a detection region in fluid communication with the plurality of mixer regions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
-
Specification