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Processes for the preparation of 2-aminomethlpyridines and the 2-cyanopyridines used in their preparation

  • US 6,921,828 B2
  • Filed: 08/21/2001
  • Issued: 07/26/2005
  • Est. Priority Date: 08/25/2000
  • Status: Expired due to Term
First Claim
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1. A process for the preparation of a compound of general formula (I):

  • embedded imageor a salt thereof,which process comprises the catalytic hydrogenation of a compound of general formula (II);

    embedded imageor a salt thereof,wherein X is halogen;

    each Y, which may be the same or different, is halogen, haloalkyl, alkoxycarbonyl or alkylsulphonyl; and

    n is 0 to 3, in the presence of a catalyst comprising palladium;

    in a solvent and at a temperature in the range of from 0°

    C. to 60°

    C.

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