Implantable cardiac stimulation system and method for measuring atrioventricular conduction and adjusting atrioventricular hystersis

• US 6,925,326 B1
• Filed: 01/04/2002
• Issued: 08/02/2005
• Est. Priority Date: 09/12/2001
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Bornzin, Gene A., Levine, Paul A.
• Primary Examiner(s): Bockelman, Mark
• Application Number:
  US10/039,414
• Time in Patent Office: 1,306 Days
• Field of Search: 607/9, 607/17, 607/7, 607/13, 607/15, 607/16, 600/509, 600/510
• US Class Current: 600/510
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

An implantable cardiac stimulation device and method measure atrioventricular conduction times and automatically adjust an atrioventricular delay time based on the measured conduction time values.

Claims

1. A method for setting an atrioventricular delay in a cardiac stimulation device, the method comprising:

monitoring for atrial events;

adjusting an atrioventricular delay until an intrinsic ventricular event is detected;

maintaining the adjusted atrioventricular delay for a predetermined number of cardiac cycles; and

storing the adjusted atrioventricular delay if at least a predetermined percentage of ventricular events during the predetermined number of cardiac cycles comprise intrinsic ventricular events.

2. The method of claim 1, wherein monitoring comprises monitoring for intrinsic atrial events.

3. The method according to claim 2, further comprising decreasing a base stimulation rate to inhibit delivery of atrial stimulation pulses;

measuring an average atrioventricular conduction time following sensing of intrinsic atrial events; and

calculating an atrial-ventricular hysteresis based on the measured average atrioventricular conduction time.

4. The method of claim 1, wherein monitoring comprises monitoring for stimulated atrial events.

5. The method according to claim 4, further comprising increasing a base stimulation rate to induce delivery of atrial stimulation pulses;

measuring an average atrioventricular conduction time following delivery of atrial stimulation pulses; and

calculating an atrial-ventricular hysteresis based on the measured average atrioventricular conduction time.

6. The method of claim 1, wherein adjusting an atrioventricular delay comprises adjusting a hysteresis value.

7. The method according to claim 6, wherein adjusting the atrial-ventricular hysteresis comprises:

calculating an average atrioventricular conduction time from a plurality of atrioventricular conduction time measurements;

calculating a measure of variability of the atrioventricular conduction time measurements; and

calculating the hysteresis value based on the average atrioventricular conduction time and the measure of variability of the atrioventricular conduction time measurements.

8. The method according to claim 1, further comprising determining an atrioventricular delay on a periodic basis.

26. The method according to claim 1 further comprising determining an atrioventricular hysteresis in accordance with the stored atrioventricular delay.

27. The method according to claim 1 further comprising

further adjusting the atrioventricular delay if a predetermined percentage of ventricular events during the predetermined number of cardiac cycles comprise paced ventricular events.

9. A cardiac stimulation device for automatically measuring an atrioventricular conduction time, comprising:

means for monitoring for atrial events;

means for monitoring for intrinsic ventricular events;

means for determining atrioventricular conduction times for a plurality of cardiac cycles;

means for determining, based on the atrioventricular conduction times, a conduction time value for which at least a predetermined percentage of ventricular events that occur during the plurality of cardiac cycles comprise intrinsic ventricular events; and

means for setting an atrioventricular delay to a value based on the conduction time value.

10. The stimulation device of claim 9, wherein the means for monitoring monitors for intrinsic atrial events.

11. The stimulation device of claim 9, wherein the means for monitoring monitors for stimulated atrial events.

12. The stimulation device according to claim 9, further comprising means for reducing a base stimulation rate to inhibit atrial stimulation;

and means for measuring atrioventricular conduction times following detected intrinsic atrial events and for calculating an atrial-ventricular hysteresis based on the measured atrioventricular conduction times.

13. The stimulation device according to claim 9, further comprising means for increasing a base stimulation rate to induce delivery of atrial stimulation, and means for measuring atrial-ventricular conduction times following delivery of atrial stimulation pulses, and for calculating an atrial-ventricular hysteresis based on the measured atrioventricular conduction times.

14. A method of measuring atrioventricular conduction times in an implantable cardiac stimulation device, the method comprising:

recording a conduction time between each of a plurality of atrial events and corresponding ventricular events;

determining a conduction time value by which at least a predetermined percentage of the ventricular events comprise intrinsic ventricular events; and

setting an atrioventricular delay to the conduction time value.

15. The method of claim 14, wherein recording comprises recording a plurality of conduction times between intrinsic atrial events and corresponding intrinsic ventricular events.

16. The method of claim 14, wherein recording comprises recording a plurality of conduction times between stimulated atrial events and corresponding intrinsic ventricular events.

17. The method of claim 14, wherein determining comprises processing the conduction times to generate statistical information relating to the conduction time values.

18. The method of claim 17, wherein the statistical information comprises an average conduction time and a measure of variability of the conduction times.

19. The method of claim 18, wherein the conduction time value is set to a value based on the average conduction time and the measure of variability.

20. The method of claim 14, wherein setting the atrioventricular delay comprises adjusting a hysteresis value to adjust the atrioventricular delay.

21. A cardiac stimulation device comprising:

monitoring circuitry that is operative to monitor for atrial events and for corresponding intrinsic ventricular events;

processing circuitry that is operative to determine an atrioventricular conduction time for each of a plurality of the monitored atrial events and corresponding monitored intrinsic ventricular events;

determining circuitry that is operative to determine a conduction time value by which at least a predetermined percentage of intrinsic ventricular events have occurred; and

control circuitry that is operative to set an atrioventricular delay to a value based on the conduction time value.

22. The stimulation device of claim 21, wherein the monitoring circuitry monitors for intrinsic atrial events.

23. The stimulation device of claim 21, wherein the monitoring circuitry monitors for stimulated atrial events.

24. The stimulation device according to claim 21, wherein the control circuitry is operative to set the atrioventricular delay to the conduction time value.

25. The stimulation device of claim 21 further comprising a processor that comprises at least one of the processing circuitry, determining circuitry and control circuitry.

28. A method for setting an atrioventricular delay in a cardiac stimulation device, the method comprising:

monitoring for atrial events;

adjusting an atrioventricular delay until an intrinsic ventricular event is detected;

maintaining the adjusted atrioventricular delay for a predetermined number of cardiac cycles; and

further adjusting the atrioventricular delay if a predetermined percentage of ventricular events during the predetermined number of cardiac cycles comprise paced ventricular events.