Left and right side heart support

• US 6,926,662 B1
• Filed: 12/23/1999
• Issued: 08/09/2005
• Est. Priority Date: 12/23/1998
• Status: Expired due to Term

• Current Assignee: Maquet Cardiovascular LLC (Getinge AB)
• Original Assignee: A-Med Systems, Inc.
• Inventors: Kanz, William R., Guidera, Michael, Aboul-Hosn, Walid N., Matheny, Robert G., Akin, Jodi
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US09/868,973
• Time in Patent Office: 2,056 Days
• Field of Search: 600/16, 600/17, 623/3.1, 623/11.1, 623/904, 623/910, 623/913, 623/922, 623/3.26, 623/3.3
• US Class Current: 600/16
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/3663 Flow rate transducers; Flow integrators
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/17 inside a ventricle, e.g. intraventricular balloon pumps
• CPC Class Codes: A61M 60/183 drawing blood from both ventricles, e.g. bi-ventricular assist devices [BiVAD]
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/237 the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
• CPC Class Codes: A61M 60/279 Peristaltic pumps, e.g. roller pumps
• CPC Class Codes: A61M 60/894 Passive valves, i.e. valves actuated by the blood

Abstract

A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.

Claims

1. A cannulation system for cardiac support comprising:

an inner cannula disposed within an outer cannula, the outer cannula including a fluid inlet sized and configured for placement within the right atrium of a heart, the inner cannula including a fluid inlet sized and configured to extend through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart; and

a pumping assembly coupled to the inner and outer cannulas and adapted to perform at least one of withdrawing blood from the right atrium for delivery to the pulmonary artery to provide right heart support, and withdrawing blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support,

wherein the outer cannula is equipped with a dilator member extending distally from the fluid inlet of the outer cannula adapted to facilitate passing the fluid inlet of the inner cannula through the atrial septum for positioning within the left side of the heart;

wherein the pumping assembly includes a pump coupled to the inner cannula to withdraw blood from the left side of the heart, and an outflow cannula coupled to the pump and adapted to extend into the aorta for delivering the withdrawn blood into the aorta to provide left heart support.

3. The cannulation system of claim 1 or 2 and further, wherein the inner cannula is equipped with an inflation member near its distal end to facilitate positioning the fluid inlet of the inner cannula within the left side of the heart.

4. The cannulation system of claim 1 or 2 and further, wherein the inner cannula is equipped with at least one of an illumination system, a pressure sensing system, an oxygenation sensing system, and a flow rate sensing system.

5. The cannulation system of claim 1 or 2 and further, wherein the outer cannula is equipped with at least one of an illumination system, a pressure sensing system, an oxygenation sensing system, and a flow rate sensing system.

6. The cannulation system of claim 1 or 2 and further, wherein the dilator member of the outer cannula is equipped with an inflatable cuff assembly adapted for securing the dilator member in position through the atrial septum and sealing the aperture formed in the atrial septum by the dilator member.

7. The cannulation system of claim 6 and further, wherein the inflatable cuff assembly includes a first inflation member and a second inflation member which, in use, are adapted to be deployed on either side of the atrial septum.

8. The cannulation system of claim 7 and further, wherein the inflation members are selectively deployed through the use of a fluid source coupled to the interior of the inflation members.

9. The cannulation system of claim 8 and further, wherein the inner cannula is equipped with at least one lumen formed in the wall thereof to pass fluid from the fluid source to the interior of the inflation members to selectively inflate and deflate the inflation members.

10. The cannulation system of claim 1 or 2 and further, wherein the dilator member of the outer cannula is equipped with a bucking cuff assembly adapted for securing the dilator member in position through the atrial septum and for sealing the aperture formed in the atrial septum by the dilator member.

11. The cannulation system of claim 10 and further, wherein the bucking cuff assembly comprises a fabric material capable of being selectively drawn to form a first cuff portion and a second cuff portion which, in use, are adapted to be deployed on either side of the atrial septum.

12. The cannulation system of claim 11 and further, wherein the fabric material of the buckling cuff assembly is drawn to form the first and second cuff portions through the use of at least one wire extending within at least one lumen formed in the wall of the outer cannula.

13. The cannulation system of claim 1 or 2 and further, including a supplemental perfusion assembly for diverting blood from the heart to a target vessel on the heart.

14. The cannulation system of claim 13 and further, wherein the supplemental perfusion assembly includes a perfusion conduit communicatively coupled to the pumping system to divert a portion of the blood being withdrawn from one of the right and left side of the heart for delivery into the target vessel.

15. The cannulation system of claim 1 or 2 and further, wherein a fluid delivery system is provided for selectively transporting fluid other than blood into the aorta.

16. The cannulation system of claim 15 and further, wherein the fluid to be delivered into the aorta is cardioplegia.

2. A cannulation system for cardiac support comprising:

an inner cannula disposed within an outer cannula, the outer cannula including a fluid inlet sized and configured for placement within the right atrium of a heart, the inner cannula including a fluid inlet sized and configured to extend through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart; and

a pumping assembly coupled to the inner and outer cannulas and adapted to perform at least one of withdrawing blood from the right atrium for delivery to the pulmonary artery to provide right heart support, and withdrawing blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support,

wherein the outer cannula is equipped with a dilator member extending distally from the fluid inlet of the outer cannula adapted to facilitate passing the fluid inlet of the inner cannula through the atrial septum for positioning within the left side of the heart, and

wherein the pumping assembly includes a pump coupled to the outer cannula adapted to withdraw blood from the right side of the heart, and an outflow cannula coupled to the pump and adapted to extend into the pulmonary artery for delivering the withdrawn blood into the pulmonary artery to provide right heart support.

17. A cannulation system for cardiac support comprising

an inner cannula disposed within an outer cannula, the outer cannula including a fluid inlet sized and configured for placement within the right atrium of a heart, the inner cannula including a fluid inlet sized and configured to extend through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart;

and

a pumping assembly coupled to the inner and outer cannulas and adapted to perform at least one of withdrawing blood from the right atrium for delivery to the pulmonary artery to provide right heart support, and withdrawing blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support,

wherein the pumping assembly includes a pump coupled to the inner cannula to withdraw blood from the left side of the heart, and an outflow cannula coupled to the pump and adapted to extend into the aorta for delivering the withdrawn blood into the aorta to provide left heart support, and

wherein the outflow cannula from the pump is equipped with an inflation member near its distal end adapted to selectively occlude the aorta.

18. The cannulation system of claim 17 and further, wherein the inflation member is selectively deployed through the use of a fluid source coupled to the interior of the inflation member.

19. The cannulation system of claim 18 and further, wherein the outflow cannula from the pump is equipped with at least one lumen formed in the wall thereof to pass fluid from the fluid source to the interior of the inflation member to selectively inflate and deflate the inflation member.

20. A cannulation system for cardiac support comprising:

an inner cannula disposed within an outer cannula, the outer cannula including a fluid inlet sized and configured for placement within the right atrium of a heart, the inner cannula including a fluid inlet sized and configured to extend through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart; and

a pumping assembly coupled to the inner and outer cannulas and adapted to perform at least one of withdrawing blood from the right atrium for delivery to the pulmonary artery to provide right heart support, and withdrawing blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support;

wherein the pumping assembly includes a pump coupled to the outer cannula to withdraw blood from the right side of the heart, and an outflow cannula coupled to the pump and adapted to extend into the pulmonary artery for delivering the withdrawn blood into the pulmonary artery to provide right heart support; and

wherein the outflow cannula coupled to the pump comprises a second inner cannula that is adapted to extend from the pump, through the outer cannula, and out the fluid inlet of the outer cannula such that a fluid outlet of the second inner cannula is disposed within the pulmonary artery.

21. The cannulation system of claim 20 and further, wherein the outer cannula includes a curved conduit extending distally from the fluid inlet through which the second inner cannula is adapted to pass in order to position the fluid outlet of the second inner cannula in the pulmonary artery.