Stents, stenting systems, and related methods for agent delivery
First Claim
1. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,a tubular member having a lumen there through to allow the passage of material, wherein the tubular member may be expanded causing the stenting system to be retained against the wall of the body lumen;
- an outer membrane surrounding the tubular member, wherein at least a portion of the outer membrane is porous to the agent to allow the agent to be deposited on the site;
an inner membrane attached to the tubular member, wherein the inner membrane is non-porous to the therapeutic agent to be delivered to the site; and
a chamber located between the inner and outer membranes for holding the agent, wherein the agent in the chamber diffuses through the porous portion of the outer membrane and onto the body site.
2 Assignments
0 Petitions
Accused Products
Abstract
A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.
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Citations
22 Claims
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1. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,
a tubular member having a lumen there through to allow the passage of material, wherein the tubular member may be expanded causing the stenting system to be retained against the wall of the body lumen; -
an outer membrane surrounding the tubular member, wherein at least a portion of the outer membrane is porous to the agent to allow the agent to be deposited on the site;
an inner membrane attached to the tubular member, wherein the inner membrane is non-porous to the therapeutic agent to be delivered to the site; and
a chamber located between the inner and outer membranes for holding the agent, wherein the agent in the chamber diffuses through the porous portion of the outer membrane and onto the body site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,
an inner tubular member having a lumen there through for the passage of material; -
a membrane surrounding the inner tubular member;
an outer tubular member surrounding the inner tubular member and the membrane; and
a porous member forming at least a portion of the outer tubular member, wherein the membrane and the outer tubular member define a chamber there between for holding the agent, wherein the agent in the chamber may pass through the porous member of the outer tubular member and be deposited directly on the body site, and wherein the membrane is non-porous to the agent thereby isolating the lumen of inner tubular member from the agent in the chamber. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A system for delivering an agent to a body site comprising:
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an expandable tube having a lumen there through, wherein the sides of the tube have openings therein to allow passage of material through the lumen;
an outer membrane surrounding the expandable tube and forming a chamber with a surface of the expandable tube, wherein at least a portion of the membrane is porous to the agent allowing diffusion of the agent there through to the body site, and wherein the expandable tube prevents the agent from diffusing from the chamber and into the lumen of the expandable tube; and
an opening in the chamber allowing delivery of the agent to the chamber. - View Dependent Claims (18, 19, 20, 21, 22)
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Specification