Device having a flow channel
First Claim
1. A sensor strip comprising:
- (a) a base layer having a first major surface and a second major surface;
(b) a cover layer having a first major surface and a second major surface, the first major surface of said cover layer facing the first major surface of said base layer;
(c) a spacer layer interposed between the first major surface of said cover layer and the first major surface of said base layer to separate said cover layer from said base layer;
(d) a flow channel having walls formed by said first major surface of said cover layer, said first major surface of said base layer, and said spacer layer, said flow channel having a reaction site therein, wherein said reaction site includes an electrode arrangement, said flow channel being of such dimensions that a liquid sample can be drawn therein and can flow therethrough by means of capillary attraction;
(e) a flow-terminating interface applied to or formed in said first major surface of said cover layer, said flow-terminating interface capable of terminating flow of a sample of liquid in said flow channel at said flow-terminating interface;
(f) a sample application zone, where a liquid sample is introduced into said flow channel; and
(g) at least one opening communicating with said flow channel to allow gas to be vented from said flow channel.
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Accused Products
Abstract
A device having a flow channel, wherein at least one flow-terminating interface is used to control the flow of liquid in the flow channel. The flow-terminating interface prevents the flow of the liquid beyond the interface. In one aspect, the invention provides a sensor, such as, for example, a biosensor, in the form of a strip, the sensor being suitable for electrochemical or optical measurement. The sensor comprises a base layer and a cover layer, and the base layer is separated from the cover layer by a spacer layer. The base layer, cover layer, and spacer layer define a flow channel into which a liquid sample is drawn therein and flows therethrough by means of capillary attraction. The flow of the sample is terminated by a flow-terminating interface positioned in the flow channel.
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Citations
23 Claims
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1. A sensor strip comprising:
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(a) a base layer having a first major surface and a second major surface;
(b) a cover layer having a first major surface and a second major surface, the first major surface of said cover layer facing the first major surface of said base layer;
(c) a spacer layer interposed between the first major surface of said cover layer and the first major surface of said base layer to separate said cover layer from said base layer;
(d) a flow channel having walls formed by said first major surface of said cover layer, said first major surface of said base layer, and said spacer layer, said flow channel having a reaction site therein, wherein said reaction site includes an electrode arrangement, said flow channel being of such dimensions that a liquid sample can be drawn therein and can flow therethrough by means of capillary attraction;
(e) a flow-terminating interface applied to or formed in said first major surface of said cover layer, said flow-terminating interface capable of terminating flow of a sample of liquid in said flow channel at said flow-terminating interface;
(f) a sample application zone, where a liquid sample is introduced into said flow channel; and
(g) at least one opening communicating with said flow channel to allow gas to be vented from said flow channel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A device for allowing the flow of a liquid and for terminating the flow of said liquid, said device comprising;
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(a) a flow channel bounded by a wall, said flow channel having dimensions to allow a liquid to flow by capillary attraction; and
(b) a flow-terminating interface to terminate the flow of said liquid in said flow channel at said flow-terminating interface, wherein said flow-terminating interface comprises a plurality of openings in said wall of said flow channel.
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Specification